Abstract
The mucosal neuroma syndrome is characterised by a typical physical appearance, neuromata on tongue and buccal mucosa, and a high risk of developing medullary thyroid carcinoma and phaeochromocytoma. A case is described and the importance of early recognition for prevention of malignancy is stressed.
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- Brown R. S., Colle E., Tashjian A. H., Jr The syndrome of multiple aucosal neuromas and medullary thyroid carcinoma in childhood. Importance of recognition of the phenotype for the early detection of malignancy. J Pediatr. 1975 Jan;86(1):77–83. doi: 10.1016/s0022-3476(75)80708-6. [DOI] [PubMed] [Google Scholar]
- Graze K., Spiler I. J., Tashjian A. H., Jr, Melvin K. E., Cervi-Skinner S., Gagel R. F., Miller H. H., Wolfe H. J., DeLellis R. A., Leape L. Natural history of familial medullary thyroid carcinoma: effect of a program for early diagnosis. N Engl J Med. 1978 Nov 2;299(18):980–985. doi: 10.1056/NEJM197811022991804. [DOI] [PubMed] [Google Scholar]
- Khairi M. R., Dexter R. N., Burzynski N. J., Johnston C. C., Jr Mucosal neuroma, pheochromocytoma and medullary thyroid carcinoma: multiple endocrine neoplasia type 3. Medicine (Baltimore) 1975 Mar;54(2):89–112. [PubMed] [Google Scholar]
- Moyes C. D., Alexander F. W. Mucosal neuroma syndrome presenting in a neonate. Dev Med Child Neurol. 1977 Aug;19(4):518–534. doi: 10.1111/j.1469-8749.1977.tb07947.x. [DOI] [PubMed] [Google Scholar]
- Norton J. A., Froome L. C., Farrell R. E., Wells S. A., Jr Multiple endocrine neoplasia type IIb: the most aggressive form of medullary thyroid carcinoma. Surg Clin North Am. 1979 Feb;59(1):109–118. doi: 10.1016/s0039-6109(16)41737-8. [DOI] [PubMed] [Google Scholar]