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. 1986 Oct;61(10):1020–1023. doi: 10.1136/adc.61.10.1020

Response to bronchodilators assessed by lung mechanics.

A Greenough, B G Loftus, J Pool, J F Price
PMCID: PMC1777965  PMID: 3535685

Abstract

Abnormalities of compliance and functional residual capacity were shown in eight young children aged 2-8 years with asthma during an acute attack. In a randomised, placebo controlled study treatment with bronchodilator (salbutamol) was associated with a significant improvement in compliance and lessening of hyperinflation as shown by a reduction in functional residual capacity.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Chai H., Purcell K., Brady K., Falliers C. J. Therapeutic and investiational evaluation of asthmatic children. J Allergy. 1968 Jan;41(1):23–36. doi: 10.1016/0021-8707(68)90005-1. [DOI] [PubMed] [Google Scholar]
  2. Cogswell J. J. Forced oscillation technique for determination of resistance to breathing in children. Arch Dis Child. 1973 Apr;48(4):259–266. doi: 10.1136/adc.48.4.259. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Groggins R. C., Lenney W., Milner A. D., Stokes G. M. Efficacy of orally administered salbutamol and theophylline in pre-schoolchildren with asthma. Arch Dis Child. 1980 Mar;55(3):204–206. doi: 10.1136/adc.55.3.204. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Groggins R. C., Milner A. D., Stokes G. M. Bronchodilator effects of clemastine, ipratropium, bromide, and salbutamol in preschool children with asthma. Arch Dis Child. 1981 May;56(5):342–344. doi: 10.1136/adc.56.5.342. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Lenney W., Milner A. D. At what age do bronchodilator drugs work? Arch Dis Child. 1978 Jul;53(7):532–535. doi: 10.1136/adc.53.7.532. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. MARSHALL R., MCILROY M. B. The mechanical properties of the lungs in asthma. Clin Sci. 1956 May;15(2):345–351. [PubMed] [Google Scholar]
  7. Mansell A., Dubrawsky C., Levison H., Bryan A. C., Langer H., Collins-Williams C., Orange R. P. Lung mechanics in antigen-induced asthma. J Appl Physiol. 1974 Sep;37(3):297–301. doi: 10.1152/jappl.1974.37.3.297. [DOI] [PubMed] [Google Scholar]
  8. Mead J., Turner J. M., Macklem P. T., Little J. B. Significance of the relationship between lung recoil and maximum expiratory flow. J Appl Physiol. 1967 Jan;22(1):95–108. doi: 10.1152/jappl.1967.22.1.95. [DOI] [PubMed] [Google Scholar]
  9. Pearce J. L., Wesley H. M. Children with asthma: will nebulised salbutamol reduce hospital admissions? Br Med J (Clin Res Ed) 1985 Feb 23;290(6468):595–597. doi: 10.1136/bmj.290.6468.595. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Steiner N., Phelan P. D. Physiological assessment of severe chronic asthma in children. Respiration. 1978;35(1):30–36. doi: 10.1159/000193856. [DOI] [PubMed] [Google Scholar]
  11. Strachan D. P. The prevalence and natural history of wheezing in early childhood. J R Coll Gen Pract. 1985 Apr;35(273):182–184. [PMC free article] [PubMed] [Google Scholar]
  12. TOOLEY W. H., DEMUTH G., NADEL J. A. THE REVERSIBILITY OF OBSTRUCTIVE CHANGES IN SEVERE CHILDHOOD ASTHMA. J Pediatr. 1965 Mar;66:517–524. doi: 10.1016/s0022-3476(65)80116-0. [DOI] [PubMed] [Google Scholar]
  13. Warner J. O. Significance of late reactions after bronchial challenge with house dust mite. Arch Dis Child. 1976 Dec;51(12):905–911. doi: 10.1136/adc.51.12.905. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Woolcock A. J., Read J. Improvement in bronchial asthma not reflected in forced expiratory volume. Lancet. 1965 Dec 25;2(7426):1323–1325. doi: 10.1016/s0140-6736(65)92343-3. [DOI] [PubMed] [Google Scholar]
  15. Woolcock A. J., Read J. Lung volumes in exacerbations of asthma. Am J Med. 1966 Aug;41(2):259–273. doi: 10.1016/0002-9343(66)90021-0. [DOI] [PubMed] [Google Scholar]

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