Skip to main content
Archives of Disease in Childhood logoLink to Archives of Disease in Childhood
. 1987 May;62(5):440–444. doi: 10.1136/adc.62.5.440

Hydrolysed wheat based oral rehydration solution for acute diarrhoea.

A N Alam, S A Sarker, A M Molla, M M Rahaman, W B Greenough 3rd
PMCID: PMC1778371  PMID: 3300569

Abstract

A randomised three cell study was carried out in 78 children with acute diarrhoea to evaluate the relative efficacy of oral rehydration solution (ORS) made from partially hydrolysed wheat grain, cooked rice powder, or glucose. Twenty six patients with comparable age, body weight, duration of diarrhoea, and degree of dehydration were studied in each of the three groups. Initial rehydration was carried out by using intravenous Dhaka solution within one to two hours followed by administration of oral rehydration solution. The mean ORS intake during the first and second 24 hours of treatment in patients with cholera receiving wheat-ORS and rice-ORS was significantly less compared with those receiving glucose-ORS. The stool output during the same period in patients receiving wheat-ORS and rice-ORS was significantly less compared with those receiving glucose-ORS. Similar trends in both ORS intake and stool output were observed during the next 24 hours.

Full text

PDF
440

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Chatterjee A., Mahalanabis D., Jalan K. N., Maitra T. K., Agarwal S. K., Bagchi D. K., Indra S. Evaluation of a sucrose/electrolyte solution for oral rehydration in acute infantile diarrhoea. Lancet. 1977 Jun 25;1(8026):1333–1335. doi: 10.1016/s0140-6736(77)92550-8. [DOI] [PubMed] [Google Scholar]
  2. Guerrant R. L., Brunton L. L., Schnaitman T. C., Rebhun L. I., Gilman A. G. Cyclic adenosine monophosphate and alteration of Chinese hamster ovary cell morphology: a rapid, sensitive in vitro assay for the enterotoxins of Vibrio cholerae and Escherichia coli. Infect Immun. 1974 Aug;10(2):320–327. doi: 10.1128/iai.10.2.320-327.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Hirschhorn N., Denny K. M. Oral glucose-electrolyte therapy for diarrhea: a means to maintain or improve nutrition? Am J Clin Nutr. 1975 Feb;28(2):189–192. doi: 10.1093/ajcn/28.2.189. [DOI] [PubMed] [Google Scholar]
  4. Molla A. M., Ahmed S. M., Greenough W. B., 3rd Rice-based oral rehydration solution decreases the stool volume in acute diarrhoea. Bull World Health Organ. 1985;63(4):751–756. [PMC free article] [PubMed] [Google Scholar]
  5. Molla A. M., Sarker S. A., Hossain M., Molla A., Greenough W. B., 3rd Rice-powder electrolyte solution as oral-therapy in diarrhoea due to Vibrio cholerae and Escherichia coli. Lancet. 1982 Jun 12;1(8285):1317–1319. doi: 10.1016/s0140-6736(82)92396-0. [DOI] [PubMed] [Google Scholar]
  6. Morris G. K., Merson M. H., Sack D. A., Wells J. G., Martin W. T., Dewitt W. E., Feeley J. C., Sack R. B., Bessudo D. M. Laboratory investigation of diarrhea in travelers to Mexico: evaluation of methods for detecting enterotoxigenic Echerichia coli. J Clin Microbiol. 1976 May;3(5):486–495. doi: 10.1128/jcm.3.5.486-495.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Nalin D. R., Cash R. A., Islam R., Molla M., Phillips R. A. Oral maintenance therapy for cholera in adults. Lancet. 1968 Aug 17;2(7564):370–373. doi: 10.1016/s0140-6736(68)90591-6. [DOI] [PubMed] [Google Scholar]
  8. Palmer D. L., Koster F. T., Islam A. F., Rahman A. S., Sack R. B. Comparison of sucrose and glucose in the oral electrolyte therapy of cholera and other severe diarrheas. N Engl J Med. 1977 Nov 17;297(20):1107–1110. doi: 10.1056/NEJM197711172972007. [DOI] [PubMed] [Google Scholar]
  9. Patra F. C., Mahalanabis D., Jalan K. N., Sen A., Banerjee P. Is oral rice electrolyte solution superior to glucose electrolyte solution in infantile diarrhoea? Arch Dis Child. 1982 Dec;57(12):910–912. doi: 10.1136/adc.57.12.910. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Suthutvoravut U., Tontisirin K., Varavithya W., Valyasevi A., Björck I., Dahlqvist A. Wheat extract and milk mixture as a milk substitute for children with milk intolerance. J Diarrhoeal Dis Res. 1984 Sep;2(3):168–172. [PubMed] [Google Scholar]
  11. Yolken R. H., Kim H. W., Clem T., Wyatt R. G., Kalica A. R., Chanock R. M., Kapikian A. Z. Enzyme-linked immunosorbent assay (ELISA) for detection of human reovirus-like agent of infantile gastroenteritis. Lancet. 1977 Aug 6;2(8032):263–267. doi: 10.1016/s0140-6736(77)90951-5. [DOI] [PubMed] [Google Scholar]

Articles from Archives of Disease in Childhood are provided here courtesy of BMJ Publishing Group

RESOURCES