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. 1988 Oct;63(10):1184–1188. doi: 10.1136/adc.63.10.1184

Single photon emission computed tomography in seizure disorders.

R Denays 1, M Rubinstein 1, H Ham 1, A Piepsz 1, P Noël 1
PMCID: PMC1779044  PMID: 3264135

Abstract

Fourteen children with various seizure disorders were studied using a cerebral blood flow tracer, 123I iodoamphetamine (0.05 mCi/kg), and single photon emission computed tomography (SPECT). In the five patients with radiological lesions, SPECT showed congruent or more extensive abnormalities. Five of the nine children with a normal scan on computed tomography had abnormal SPECT studies consisting of focal hypoperfusion, diffuse hemispheric hypoperfusion, multifocal and bilateral hypoperfusion, or focal hyperperfusion. A focal lesion seen on SPECT has been found in children with tonic-clonic seizures suggesting secondarily generalised seizures. Moreover the pattern seen on SPECT seemed to be related to the clinical status. An extensive impairment found on SPECT was associated with a poor evolution in terms of intellectual performance and seizure frequency. Conversely all children with a normal result on SPECT had less than two seizures per year and normal neurological and intellectual development.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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