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. 1996 May;178(9):2715–2717. doi: 10.1128/jb.178.9.2715-2717.1996

Integration host factor amplifies the induction of the aceBAK operon of Escherichia coli by relieving IclR repression.

E Resnik 1, B Pan 1, N Ramani 1, M Freundlich 1, D C LaPorte 1
PMCID: PMC178001  PMID: 8626344

Abstract

A binding site for integration host factor (IHF) was identified upstream of the aceBAK promoter. Under inducing conditions, IHF activates aceB::lacZ expression by opposing IclR repression. In contrast, IHF has little effect on aceB::lacZ expression under repressing conditions. The ability of IHF to relieve repression under inducing but not repressing conditions allows this protein to amplify the induction of aceBAK.

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Selected References

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