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CD32 ligation does not inhibit interleukin-4 (IL-4)/anti-CD40 monoclonal antibody (mAb)-induced immunoglobulin E (IgE) germline gene transcription. BL-2 cells, transfected with an IgE germline promoter luciferase construct, were stimulated with IL-4 and anti-CD40 mAb for 48 hr in the absence or presence of CD32 antibody (µg/ml) before luciferase was measured.
