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Receptor-mediated endocytosis by immature and mature monocyte-derived dendritic cells (MoDCs) and MUTZ-3 DCs. Fluorescein isothiocyanate (FITC)-dextran uptake at 37° by immature (a) and mature (b) MoDCs compared with the uptake at 0° (grey) was calculated, using the mean fluorescence intensity (MFI). The uptake of FITC-dextran by immature (c) and mature (d) MUTZ-3 DCs demonstrated a similar reduction of antigen uptake compared with MoDCs. ΔMFI is based on the geometric mean value.
