Table 2.
Human omenta | ||||
---|---|---|---|---|
JH gene segment | IgVH4 + 5-IgM | IgVH4 + 5-IgA | IgVH4 + 5-IgG | Total |
JH1 | 0 | 1 | 1 | 2* |
JH2 | 0 | 0 | 0 | 0 |
JH3 | 2 | 6 | 7 | 15 |
JH4 | 9 | 13 | 13 | 35 |
JH5 | 10 | 6 | 4 | 20 |
JH6 | 3 | 10 | 5 | 18 |
Total number ofimmunoglobulintranscripts | 24 | 36 | 30 | 90 |
JH1 gene segment usage in the omentum (two of 90) compared with the intestinal mucosa and parotid salivary gland (zero of 324) from Thoree et al.16. P = 0·007 (χ2 test). There was no significant difference in JH1 usage when compared to PBMC and spleen.