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. 1996 Aug;178(15):4742–4746. doi: 10.1128/jb.178.15.4742-4746.1996

Glutathione amide and its perthiol in anaerobic sulfur bacteria.

R G Bartsch 1, G L Newton 1, C Sherrill 1, R C Fahey 1
PMCID: PMC178251  PMID: 8755912

Abstract

Chromatium species produced the novel biological thiol glutathione amide, gamma-L-glutamyl-L-cysteinylglycine amide (GASH), when grown photoheterotrophically. GASH was largely converted to the corresponding perthiol during photoautotrophic growth on sulfide, suggesting that GASH may have a function in anaerobic sulfide metabolism. This unprecedented form of glutathione metabolism was probably present in anaerobic ancestors of modern cyanobacteria and purple bacteria.

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Selected References

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