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Naïve and CD27+ memory cells were stimulated with phytohaemagglutinin (PHA), interleukin (IL)-2 and either (a) a T helper 1 (Th1) cocktail (IL-12, anti-IL-4 and anti-IL-4R immunoglobulin) for 20 days, or (b) a T helper 2 (Th2) cocktail (IL-4 and anti-IFN-γ immunoglobulin) for 28 days. The cytokines and the antibodies in the different cocktails were distributed once weekly. The data are representative of three similar experiments.
