Figure 4.
Effect of interleukin-12 (IL-12) on concanavalin A (Con A)-stimulated spleen cell proliferation from Trypanosoma cruzi-infected (ISC) or from normal control (NSC) mice. Cultures were obtained on days 5, 9 or 12 after infection and were treated (or not treated) with NG-monomethyl-l-arginine (NMMA). Values are expressed as arithmetic means of triplicate cultures ±standard deviation. (a) NSC and ISC on day 5 of infection. (b) ISC on days 9 and 12 of infection, treated or not treated with NMMA. The results are representative of four experiments.