In the Biological Perspectives article entitled,“Hematopoietic Stem Cells: The Paradigmatic Tissue-Specific Stem Cell” (Volume 169, page 337), which appeared in the August 2006 issue of The American Journal of Pathology, the DOI (digital object identifier) was listed incorrectly in the printed version of this article. The correct DOI for this article is 10.2353/ajpath.2006.060312. This error occurred in the print article only; the online (HTML and PDF) versions of this article appear with the correct DOI.
In the article entitled, “Involvement of Endothelial CD44 during in Vivo Angiogenesis” (Volume 169, page 325), which appeared in the July 2006 issue of The American Journal of Pathology, the legend for Figure 7 appeared incorrectly. The corrected figure legend appears below.
Figure 7.
Effects of IM7.8.1 antibody on the in vitro function of murine ECs. Studies were performed of the effects of anti-CD44 antibody (IM7.8.1) on various functions of the H5V murine EC line. A: The adhesion of the H5V cells to HA-coated surfaces was inhibited by IM7.8.1 (n = 4, *P < 0.001). B: The proliferation of H5V cells cultured for 24 hours in the presence of serum was assessed using a colorimetric assay and measurement of the reaction mixture at 490 nm. IM7.8.1 did not inhibit the proliferative response (n = 4). C: Linear defects were made in confluent cell monolayers, and closure of the wounds after 24 hours was assessed by computer-assisted image analysis (n = 6). Wound-induced migration was not inhibited by IM7.8.1. D: Apoptosis was assessed after 5 hours in the absence or presence of serum with IgG or IM7.8.1. IM7.8.1 did not induce apoptosis (n = 24). E: Shown are representative images of H5V cells plated on Matrigel that demonstrate that IM7.8.1 impairs tube formation.