Skip to main content
Journal of Bacteriology logoLink to Journal of Bacteriology
. 1996 Oct;178(19):5810–5812. doi: 10.1128/jb.178.19.5810-5812.1996

Identification of LytSR-regulated genes from Staphylococcus aureus.

E W Brunskill 1, K W Bayles 1
PMCID: PMC178427  PMID: 8824633

Abstract

In this report, the characterization of a Staphylococcus aureus operon containing two LytSR-regulated genes, lrgA and lrgB, is described. Sequence and mutagenesis studies of these genes suggest that lrgA encodes a murein hydrolase exporter similar to bacteriophage holin proteins while lrgB may encode a protein having murein hydrolase activity.

Full Text

The Full Text of this article is available as a PDF (449.6 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Brunskill E. W., Bayles K. W. Identification and molecular characterization of a putative regulatory locus that affects autolysis in Staphylococcus aureus. J Bacteriol. 1996 Feb;178(3):611–618. doi: 10.1128/jb.178.3.611-618.1996. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Hart M. E., Smeltzer M. S., Iandolo J. J. The extracellular protein regulator (xpr) affects exoprotein and agr mRNA levels in Staphylococcus aureus. J Bacteriol. 1993 Dec;175(24):7875–7879. doi: 10.1128/jb.175.24.7875-7879.1993. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Henderson T. A., Templin M., Young K. D. Identification and cloning of the gene encoding penicillin-binding protein 7 of Escherichia coli. J Bacteriol. 1995 Apr;177(8):2074–2079. doi: 10.1128/jb.177.8.2074-2079.1995. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Lleò M. M., Fontana R., Solioz M. Identification of a gene (arpU) controlling muramidase-2 export in Enterococcus hirae. J Bacteriol. 1995 Oct;177(20):5912–5917. doi: 10.1128/jb.177.20.5912-5917.1995. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Young R., Bläsi U. Holins: form and function in bacteriophage lysis. FEMS Microbiol Rev. 1995 Aug;17(1-2):191–205. doi: 10.1111/j.1574-6976.1995.tb00202.x. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Bacteriology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES