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. 1996 Oct;178(20):6067–6069. doi: 10.1128/jb.178.20.6067-6069.1996

Secondary structure of the outer membrane proteins OmpA of Escherichia coli and OprF of Pseudomonas aeruginosa.

E Sugawara 1, M Steiert 1, S Rouhani 1, H Nikaido 1
PMCID: PMC178469  PMID: 8830709

Abstract

When purified without the use of ionic detergents, both OmpA and OprF proteins contained nearly 20% alpha-helical structures, which disappeared completely upon the addition of sodium dodecyl sulfate. This result suggests that the proteins fold in a similar manner, with an N-terminal, membrane-spanning beta-barrel domain and a C-terminal, globular, periplasmic domain.

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Selected References

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