Abstract
Pentaerythritol tetranitrate reductase, which reductively liberates nitrite from nitrate esters, is related to old yellow enzyme. Pentaerythritol tetranitrate reductase follows a ping-pong mechanism with competitive substrate inhibition by NADPH, is strongly inhibited by steroids, and is capable of reducing the unsaturated bond of 2-cyclohexen-1-one.
Full Text
The Full Text of this article is available as a PDF (272.4 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Binks P. R., French C. E., Nicklin S., Bruce N. C. Degradation of pentaerythritol tetranitrate by Enterobacter cloacae PB2. Appl Environ Microbiol. 1996 Apr;62(4):1214–1219. doi: 10.1128/aem.62.4.1214-1219.1996. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Fox K. M., Karplus P. A. Old yellow enzyme at 2 A resolution: overall structure, ligand binding, and comparison with related flavoproteins. Structure. 1994 Nov 15;2(11):1089–1105. [PubMed] [Google Scholar]
- French C. E., Bruce N. C. Bacterial morphinone reductase is related to Old Yellow Enzyme. Biochem J. 1995 Dec 15;312(Pt 3):671–678. doi: 10.1042/bj3120671. [DOI] [PMC free article] [PubMed] [Google Scholar]
- French C. E., Bruce N. C. Purification and characterization of morphinone reductase from Pseudomonas putida M10. Biochem J. 1994 Jul 1;301(Pt 1):97–103. doi: 10.1042/bj3010097. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Madani N. D., Malloy P. J., Rodriguez-Pombo P., Krishnan A. V., Feldman D. Candida albicans estrogen-binding protein gene encodes an oxidoreductase that is inhibited by estradiol. Proc Natl Acad Sci U S A. 1994 Feb 1;91(3):922–926. doi: 10.1073/pnas.91.3.922. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Miranda M., Ramírez J., Guevara S., Ongay-Larios L., Peña A., Coria R. Nucleotide sequence and chromosomal localization of the gene encoding the Old Yellow Enzyme from Kluyveromyces lactis. Yeast. 1995 Apr 30;11(5):459–465. doi: 10.1002/yea.320110509. [DOI] [PubMed] [Google Scholar]
- Niino Y. S., Chakraborty S., Brown B. J., Massey V. A new old yellow enzyme of Saccharomyces cerevisiae. J Biol Chem. 1995 Feb 3;270(5):1983–1991. doi: 10.1074/jbc.270.5.1983. [DOI] [PubMed] [Google Scholar]
- Saito K., Thiele D. J., Davio M., Lockridge O., Massey V. The cloning and expression of a gene encoding Old Yellow Enzyme from Saccharomyces carlsbergensis. J Biol Chem. 1991 Nov 5;266(31):20720–20724. [PubMed] [Google Scholar]
- Scrutton N. S. alpha/beta barrel evolution and the modular assembly of enzymes: emerging trends in the flavin oxidase/dehydrogenase family. Bioessays. 1994 Feb;16(2):115–122. doi: 10.1002/bies.950160208. [DOI] [PubMed] [Google Scholar]
- Stott K., Saito K., Thiele D. J., Massey V. Old Yellow Enzyme. The discovery of multiple isozymes and a family of related proteins. J Biol Chem. 1993 Mar 25;268(9):6097–6106. [PubMed] [Google Scholar]
- Vaz A. D., Chakraborty S., Massey V. Old Yellow enzyme: aromatization of cyclic enones and the mechanism of a novel dismutation reaction. Biochemistry. 1995 Apr 4;34(13):4246–4256. doi: 10.1021/bi00013a014. [DOI] [PubMed] [Google Scholar]
- White G. F., Snape J. R., Nicklin S. Biodegradation of Glycerol Trinitrate and Pentaerythritol Tetranitrate by Agrobacterium radiobacter. Appl Environ Microbiol. 1996 Feb;62(2):637–642. doi: 10.1128/aem.62.2.637-642.1996. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wise A., Brems R., Ramakrishnan V., Villarejo M. Sequences in the -35 region of Escherichia coli rpoS-dependent genes promote transcription by E sigma S. J Bacteriol. 1996 May;178(10):2785–2793. doi: 10.1128/jb.178.10.2785-2793.1996. [DOI] [PMC free article] [PubMed] [Google Scholar]