Skip to main content
British Medical Journal logoLink to British Medical Journal
. 1972 Oct 7;4(5831):7–9. doi: 10.1136/bmj.4.5831.7

Biochemical Evidence of Anxiety in Dental Patients

H D Edmondson, B Roscoe, M D Vickers
PMCID: PMC1786121  PMID: 5078436

Abstract

Urinary metabolites before dental treatment were compared in a group of patients with dental phobia and in a matched control group. Plasma adrenaline, noradrenaline, and free fatty acids were estimated before treatment, immediately after sedation with diazapam 0·2 mg/kg body weight in the phobic patients, during induction of oral anaesthesia, and during and after surgery. Patients with dental phobia had significantly higher levels of adrenaline, which were only temporarily lowered by sedation, and which during treatment remained consistently higher than those of control patients.

Full text

PDF
7

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BREGGIN P. R. THE PSYCHOPHYSIOLOGY OF ANXIETY; WITH A REVIEW OF THE LITERATURE CONCERNING ADRENALINE. J Nerv Ment Dis. 1964 Dec;139:558–568. doi: 10.1097/00005053-196412000-00009. [DOI] [PubMed] [Google Scholar]
  2. Carruthers M., Conway N., Somerville W., Taggart P., Bates D. Validity of plasma-catecholamine estimations. Lancet. 1970 Jul 11;1(7663):62–67. doi: 10.1016/s0140-6736(70)92638-3. [DOI] [PubMed] [Google Scholar]
  3. Cramp D. G., Robertson G. The fluorometric assay of triglyceride by a semiautomated method. Anal Biochem. 1968 Oct 24;25(1):246–251. doi: 10.1016/0003-2697(68)90097-3. [DOI] [PubMed] [Google Scholar]
  4. Lautch H. Dental phobia. Br J Psychiatry. 1971 Aug;119(549):151–158. doi: 10.1192/bjp.119.549.151. [DOI] [PubMed] [Google Scholar]
  5. MARTIN B. The assessment of anxiety by physiological behavioral measures. Psychol Bull. 1961 May;58:234–255. doi: 10.1037/h0045492. [DOI] [PubMed] [Google Scholar]
  6. PISANO J. J. A simple analysis for normetanephrine and metanephrine in urine. Clin Chim Acta. 1960 May;5:406–414. doi: 10.1016/0009-8981(60)90146-7. [DOI] [PubMed] [Google Scholar]
  7. ROBINSON R., RATCLIFFE J., SMITH P. A screening test for phaeochromocytoma. J Clin Pathol. 1959 Nov;12:541–543. doi: 10.1136/jcp.12.6.541. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Taggart P., Carruthers M. Endogenous hyperlipidaemia induced by emotional stress of racing driving. Lancet. 1971 Feb 20;1(7695):363–366. doi: 10.1016/s0140-6736(71)92207-0. [DOI] [PubMed] [Google Scholar]

Articles from British Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES