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. 1972 Sep 30;3(5830):797–799. doi: 10.1136/bmj.3.5830.797

Effect of Ultrasound on Chromosomes of Lymphocyte Cultures

Usama Abdulla, David Talbert, Mary Lucas, Mary Mullarkey
PMCID: PMC1786344  PMID: 5076252

Abstract

In-vitro experiments have been undertaken to assess the effect of ultrasound at diagnostic and therapeutic levels on chromosomes of human lymphocyte cultures. The frequency used was about 2 MHz. The intensity was that of diagnostic level, 23 mW/cm2, which was increased stepwise to 3·5 W/cm2. The time of exposure varied from two to eight hours. No difference could be detected between the numbers of cells with aberrations in the insonated and control cultures, but aggregation of red cells was observed at high intensities.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Abdulla U., Dewhurst C. J., Campbell S., Talbert D., Lucas M., Mullarkey M. Effect of diagnostic ultrasound on maternal and fetal chromosomes. Lancet. 1971 Oct 16;2(7729):829–831. doi: 10.1016/s0140-6736(71)90215-7. [DOI] [PubMed] [Google Scholar]
  2. Bleaney B. I., Blackbourn P., Kirkley J. Resistance of CHLF hamster cells to ultrasonic radiation of 1-5 MHz frequency. Br J Radiol. 1972 May;45(533):354–357. doi: 10.1259/0007-1285-45-533-354. [DOI] [PubMed] [Google Scholar]
  3. Bobrow M., Blackwell N., Unrau A. E., Bleaney B. Absence of any observed effect of ultrasonic irradiation on human chromosomes. J Obstet Gynaecol Br Commonw. 1971 Aug;78(8):730–736. doi: 10.1111/j.1471-0528.1971.tb01638.x. [DOI] [PubMed] [Google Scholar]
  4. Buckton K. E., Baker N. V. An investigation into possible chromosome damaging effects of ultrasound on human blood cells. Br J Radiol. 1972 May;45(533):340–342. doi: 10.1259/0007-1285-45-533-340. [DOI] [PubMed] [Google Scholar]
  5. Coakley W. T., Hughes D. E., Slade J. S., Laurence K. M. Chromosome aberrations after exposure to ultrasound. Br Med J. 1971 Jan 9;1(5740):109–110. doi: 10.1136/bmj.1.5740.109-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Coakley W. T., Slade J. S., Braeman J. M., Moore J. L. Examination of lymphocytes for chromosome aberrations after ultrasonic irradiation. Br J Radiol. 1972 May;45(533):328–332. doi: 10.1259/0007-1285-45-533-328. [DOI] [PubMed] [Google Scholar]
  7. Dyson M., Woodward B., Pond J. B. Flow of red blood cells stopped by ultrasound. Nature. 1971 Aug 20;232(5312):572–573. doi: 10.1038/232572a0. [DOI] [PubMed] [Google Scholar]
  8. Hill C. R., Joshi G. P., Revell S. H. A search for chromosome damage following exposure of Chinese hamster cells to high intensity, pulsed ultrasound. Br J Radiol. 1972 May;45(533):333–334. doi: 10.1259/0007-1285-45-533-333. [DOI] [PubMed] [Google Scholar]
  9. Lucas M., Mullarkey M., Abdulla U. Study of chromosomes in the newborn after ultrasonic fetal heart monitoring in labour. Br Med J. 1972 Sep 30;3(5830):795–796. doi: 10.1136/bmj.3.5830.795. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Macintosh I. J., Davey D. A. Relationship between intensity of ultrasound and induction of chromosome aberrations. Br J Radiol. 1972 May;45(533):320–327. doi: 10.1259/0007-1285-45-533-320. [DOI] [PubMed] [Google Scholar]
  11. Taylor K. J., Pond J. B. A study of the production of haemorrhagic injury and paraplegia in rat spinal cord by pulsed ultrasound of low megaHertz frequencies in the context of the safety for clinical usage. Br J Radiol. 1972 May;45(533):343–353. doi: 10.1259/0007-1285-45-533-343. [DOI] [PubMed] [Google Scholar]

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