Abstract
Fifteen out of 51 patients with leukaemia have produced a lymphocytotoxin in their serum which reacts with their own and a high percentage of all other lymphocytes. This is probably a protein, but not an antibody. It has been detected only before or early during cytotoxic treatment, or during a relapse. It is postulated that the lymphocytotoxin is a specific protein produced by the leukaemic cells, which may facilitate their spread in the body.
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Selected References
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- Dore J. F., Motta R., Marholev L., Hrsak I., Colas de la Noue H., Seman G., De Vassal F., Mathé G. New antigens in human leukaemic cells and antibody in the serum of leukaemic patients. Lancet. 1967 Dec 30;2(7531):1396–1398. doi: 10.1016/s0140-6736(67)93027-9. [DOI] [PubMed] [Google Scholar]
- TERASAKI P. I., MCCLELLAND J. D. MICRODROPLET ASSAY OF HUMAN SERUM CYTOTOXINS. Nature. 1964 Dec 5;204:998–1000. doi: 10.1038/204998b0. [DOI] [PubMed] [Google Scholar]