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. 1996 Dec;178(24):7322–7325. doi: 10.1128/jb.178.24.7322-7325.1996

Anaerobic production of alginate by Pseudomonas aeruginosa: alginate restricts diffusion of oxygen.

D J Hassett 1
PMCID: PMC178651  PMID: 8955420

Abstract

Pseudomonas aeruginosa produced alginate and elevated algD (encoding GDPmannose 6-dehydrogenase) transcription under strict anaerobic conditions, especially when using nitrate as a terminal electron acceptor. Purified alginate added to bacterial suspensions caused a decrease in growth, suggesting that alginate contributes to oxygen limitation for the organism and likely for patients afflicted with the inherited autosomal disease cystic fibrosis.

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Selected References

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