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. 1997 Jan;179(1):293–296. doi: 10.1128/jb.179.1.293-296.1997

Identification, sequencing, and enzymatic activity of the erythrose-4-phosphate dehydrogenase gene of Vibrio cholerae.

P A Carroll 1, G Zhao 1, S A Boyko 1, M E Winkler 1, S B Calderwood 1
PMCID: PMC178695  PMID: 8982014

Abstract

We have identified a gene in Vibrio cholerae (epd) which encodes an erythrose-4-phosphate dehydrogenase activity and is located immediately downstream of an iron-regulated virulence gene, irgA, and immediately upstream of a gene encoding phosphoglycerate kinase (pgk). Expression of epd in V. cholerae is not regulated by iron, nor is it required for virulence in an infant mouse model.

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Selected References

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