Abstract
Following a recent report that neoplasia of the lymphatic and haematopoietic tissues is commoner than average in children whose mothers have had influenza in pregnancy, the incidence of neoplasms in 1954-68 in children of the Manchester Hospital Region was examined in relation to date of birth. There were no significant differences between cohorts born in different quinquennia. Incidence among children born after six influenza epidemics in 1951-68 was no higher than among other children born in these years. It is concluded that if there is an association between maternal influenza and childhood neoplasia it is probably due to factors such as immunological deficiencies which may predispose independently to both conditions.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Doll R., Kinlen L. Immunosurveillance and cancer: epidemiological evidence. Br Med J. 1970 Nov 14;4(5732):420–422. doi: 10.1136/bmj.4.5732.420. [DOI] [PMC free article] [PubMed] [Google Scholar]
- FRY J. [Influenza A (Asian) 1957; clinical and epidemiological features in a general practice]. Br Med J. 1958 Feb 1;1(5065):259–261. doi: 10.1136/bmj.1.5065.259. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Fedrick J., Alberman E. D. Reported influenza in pregnancy and subsequent cancer in the child. Br Med J. 1972 May 27;2(5812):485–488. doi: 10.1136/bmj.2.5812.485. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Leck I. Further tests of the hypothesis that influenza in pregnancy causes malformations. HSMHA Health Rep. 1971 Mar;86(3):265–269. [PMC free article] [PubMed] [Google Scholar]
- WOODALL J., ROWSON K. E., McDONALD J. C. Age and Asian influenza, 1957. Br Med J. 1958 Nov 29;2(5108):1316–1318. doi: 10.1136/bmj.2.5108.1316. [DOI] [PMC free article] [PubMed] [Google Scholar]