Abstract
Measurements were made of total proteins, albumin, and colloid osmotic pressure on cord blood samples from 15 infants with erythroblastosis fetalis (six of whom were hydropic) and from 151 non-rhesus non-hydropic control infants. The erythroblastotic infants had levels of total protein and albumin which fell within the normal range for gestational age, but their colloid osmotic pressures were abnormally low. It seems that low colloid osmotic pressure may provide a reasonable explanation for the occurrence of hydrops fetalis.
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Selected References
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- Baum J. D., Eisenberg C., Franklin F. A., Jr, Meschia G., Battaglia F. C. Studies on colloid osmotic pressure in the fetus and newborn infant. With observations on the effects of membranes of various pore sizes. Biol Neonate. 1971;18(3):311–320. doi: 10.1159/000240371. [DOI] [PubMed] [Google Scholar]
- Driscoll S. G. Hydrops fetalis. N Engl J Med. 1966 Dec 22;275(25):1432–1434. doi: 10.1056/NEJM196612222752508. [DOI] [PubMed] [Google Scholar]
- HANSEN A. T. A self-recording electronic osmometer for quick, direct measurement of colloid osmotic pressure in small samples. Acta Physiol Scand. 1961 Nov-Dec;53:197–213. doi: 10.1111/j.1748-1716.1961.tb02278.x. [DOI] [PubMed] [Google Scholar]
- Macafee C. A., Fortune D. W., Beischer N. A. Non-immunological hydrops fetalis. J Obstet Gynaecol Br Commonw. 1970 Mar;77(3):226–237. doi: 10.1111/j.1471-0528.1970.tb03511.x. [DOI] [PubMed] [Google Scholar]
- Mancini G., Carbonara A. O., Heremans J. F. Immunochemical quantitation of antigens by single radial immunodiffusion. Immunochemistry. 1965 Sep;2(3):235–254. doi: 10.1016/0019-2791(65)90004-2. [DOI] [PubMed] [Google Scholar]
- Thumasathit B., Nondasuta A., Silpisornkosol S., Lousuebsakul B., Unchalipongse P., Mangkornkanok M. Hydrops fetalis associated with Bart's hemoglobin in northern Thailand. J Pediatr. 1968 Jul;73(1):132–138. doi: 10.1016/s0022-3476(68)80052-6. [DOI] [PubMed] [Google Scholar]
