Abstract
An intradermal jet injector was used to administer combined diphtheria, tetanus, and pertussis (D.T.P.) vaccines to infants aged 2 to 12 months. A second dose was given one month after the first and a third six months after the second. Each dose was considerably smaller than the standard intramuscular dose. Blood samples taken one month after the third dose showed a satisfactory diphtheria and tetanus antitoxin response in all but a few cases. The antibody response to the pertussis component was not examined. Reactions were insignificant. Intradermal jet injection is proposed as a cheap, extremely rapid, and effective technique for D.T.P. immunization, especially suitable for use in remote areas where trained staff and facilities are few and many children require immunization.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Haire M., Dane D. S., Dick G., Briggs E. M., Connor T. J. Further studies with a diphtheria-tetanus-poliomyelitis vaccine. J Hyg (Lond) 1966 Dec;64(4):485–488. doi: 10.1017/s0022172400040791. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Stanfield J. P., Bracken P. M. Measles vaccination: studies in methods and cost reduction in developing countries. Trans R Soc Trop Med Hyg. 1971;65(5):620–628. doi: 10.1016/0035-9203(71)90046-0. [DOI] [PubMed] [Google Scholar]