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. 1972 Apr 22;2(5807):183–188. doi: 10.1136/bmj.2.5807.183

Histological Evidence of Tumour Rejection After Active Immunotherapy in Human Malignant Disease

Geoffrey Taylor, J L I Odili
PMCID: PMC1787938  PMID: 4336763

Abstract

Active immunotherapy with multiple doses of tumour homogenate incorporated in complete Freund adjuvant was used to treat 12 patients with advanced malignant disease. Evidence of some tumour destruction was observed in 10. Improvement in general clinical condition and the disappearance of symptoms referable to tumour occurred in seven of the patients. The duration of improvement varied considerably. Histological evidence of lymphocytic infiltration, necrosis, and fibrous replacement of tumour tissue is presented.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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