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. 1972 Jun 10;2(5814):644–648. doi: 10.1136/bmj.2.5814.644

Venous Graft Surgery in Treatment of Coronary Heart Disease

Donald Ross, Richard Sutton, John Dow, Lorenzo Gonzalez-Lavin, Grady Hendrix, Keith Jefferson, Lawson McDonald, Michael Petch, Charles Smithen, Edgar Sowton
PMCID: PMC1788429  PMID: 4537450

Abstract

Sixty-seven patients have had aortocoronary venous graft bypass surgery by one surgeon for the relief of symptoms of severe coronary heart disease, including eight emergency operations. The overall operative, hospital, and late mortality was low in patients with favourable myocardial function and no previous myocardial infarction. There was a 7% mortality in patients with a normal preoperative chest radiogram, 8% mortality when the left ventricular end-diastolic pressure was normal preoperatively, and a 5% mortality in patients who had normal left ventricular angiograms. The overall mortality in all elective operations for cardiac pain resistant to medical treatment was 15·8%. 89% of survivors improved; 67% are pain-free. Exercise tolerance in survivors is increased by 135%, atrial pacing results are improved by 10%. Left ventricular end-diastolic pressure is unchanged. Left ventricular function on angiography is improved. The improvement in left ventricular function assessed objectively correlates positively with vein-graft patency, as does freedom from angina pectoris.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Berger R. L., Stary H. C. Anatomic assessment of operability by the saphenous-vein bypass operation in coronary-artery disease. N Engl J Med. 1971 Jul 29;285(5):248–252. doi: 10.1056/NEJM197107292850502. [DOI] [PubMed] [Google Scholar]
  2. Effler D. B., Favaloro R. G., Groves L. K., Loop F. D. The simple approach to direct coronary artery surgery. Cleveland Clinic experience. J Thorac Cardiovasc Surg. 1971 Oct;62(4):503–510. [PubMed] [Google Scholar]
  3. Favaloro R. G. Saphenous vein autograft replacement of severe segmental coronary artery occlusion: operative technique. Ann Thorac Surg. 1968 Apr;5(4):334–339. doi: 10.1016/s0003-4975(10)66351-5. [DOI] [PubMed] [Google Scholar]
  4. Fredrickson D. S., Levy R. I., Lees R. S. Fat transport in lipoproteins--an integrated approach to mechanisms and disorders. N Engl J Med. 1967 Jan 19;276(3):148–contd. doi: 10.1056/NEJM196701192760305. [DOI] [PubMed] [Google Scholar]
  5. Grondin C. M., Castonguay Y. R., Lepage G., Meere C., Grondin P. Aortocoronary bypass grafts. Early postoperative angiographic evaluation and reexploration for stenosis or thrombosis of the vein graft. Arch Surg. 1971 Nov;103(5):535–538. doi: 10.1001/archsurg.1971.01350110033004. [DOI] [PubMed] [Google Scholar]
  6. Johnson W. D., Flemma R. J., Lepley D., Jr, Ellison E. H. Extended treatment of severe coronary artery disease: a total surgical approach. Ann Surg. 1969 Sep;170(3):460–470. doi: 10.1097/00000658-196909010-00014. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Judkins M. P. Selective coronary arteriography. I. A percutaneous transfemoral technic. Radiology. 1967 Nov;89(5):815–824. doi: 10.1148/89.5.815. [DOI] [PubMed] [Google Scholar]
  8. Rees G., Bristow J. D., Kremkau E. L., Green G. S., Herr R. H., Griswold H. E., Starr A. Influence of aortocoronary bypass surgery on left ventricular performance. N Engl J Med. 1971 May 20;284(20):1116–1120. doi: 10.1056/NEJM197105202842002. [DOI] [PubMed] [Google Scholar]
  9. Reul G. J., Morris G. C., Jr, Howell J. F., Crawford E. S., Sandiford F. M., Wukasch D. C. The safety of ischemic cardiac arrest in distal coronary artery bypass. J Thorac Cardiovasc Surg. 1971 Oct;62(4):511–521. [PubMed] [Google Scholar]
  10. Ross R. S. The aortocoronary bypass operation. N Engl J Med. 1971 May 20;284(20):1153–1154. doi: 10.1056/NEJM197105202842010. [DOI] [PubMed] [Google Scholar]
  11. Sowton G. E., Balcon R., Cross D., Frick M. H. Measurement of the angina threshold using atrial pacing. A new technique for the study of angina pectoris. Cardiovasc Res. 1967 Oct;1(4):301–307. doi: 10.1093/cvr/1.4.301. [DOI] [PubMed] [Google Scholar]
  12. Spencer F. C., Green G. E., Tice D. A., Glassman E. Bypass grafting for occlusive disease of the coronary arteries: a report of experience with 195 patients. Ann Surg. 1971 Jun;173(6):1029–1044. doi: 10.1097/00000658-197106010-00022. [DOI] [PMC free article] [PubMed] [Google Scholar]

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