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. 1997 Feb;179(4):1404–1408. doi: 10.1128/jb.179.4.1404-1408.1997

Identification of the epitope for a highly cross-reactive monoclonal antibody on the major sigma factor of bacterial RNA polymerase.

M J Breyer 1, N E Thompson 1, R R Burgess 1
PMCID: PMC178843  PMID: 9023229

Abstract

A highly cross-reactive monoclonal antibody (MAb), 2G10, was found to react in a conserved region of Escherichia coli RNA polymerase sigma70. The epitope was localized to amino acids 470 to 486, which included part of conserved region 3.1. The epitope for MAb 3D3, a MAb which maps close to the 2G10 epitope, was also determined.

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Selected References

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