Abstract
The use of megestrol acetate to stop urine spraying in castrated male cats Four castrated male cats were treated with megestrol acetate because they were showing signs of urine spraying. The dosage used was 5 mg a day for seven days followed by 5 mg every three days for 21 days. The treatment did not exceed one month.
Treatment was successful in three of the four animals with this therapeutic regime. A relapse was noticed one year after the initial treatment in two of these cats. Treatment was resumed in one case, while in the other case spontaneous regression of urine spraying occurred. No relapse have been reported after six months.
Other methods of treatment used to suppress this undesirable behavior are also discussed.
Full text
PDF

Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Gerber H. A., Jöchle W., Sulman F. G. Control of reproduction and of undesirable social and sexual behaviour in dogs and cats. J Small Anim Pract. 1973 Mar;14(3):151–158. doi: 10.1111/j.1748-5827.1973.tb06910.x. [DOI] [PubMed] [Google Scholar]
- Hart B. L., Barrett R. E. Effects of castration on fighting, roaming, and urine spraying in adult male cats. J Am Vet Med Assoc. 1973 Aug 1;163(3):290–292. [PubMed] [Google Scholar]
- Hart B. L. Objectionable urine spraying and urine marking in cats: evaluation of progestin treatment in gonadectomized males and females. J Am Vet Med Assoc. 1980 Sep 15;177(6):529–533. [PubMed] [Google Scholar]
- Hart B. L., Voith V. L. Changes in urine spraying, feeding and sleep behavior of cats following medial preoptic-anterior hypothalamic lesions. Brain Res. 1978 Apr 28;145(2):406–409. doi: 10.1016/0006-8993(78)90877-6. [DOI] [PubMed] [Google Scholar]
- Stabenfeldt G. H. Physiologic, pathologic and therapeutic roles of progestins in domestic animals. J Am Vet Med Assoc. 1974 Feb 1;164(3):311–317. [PubMed] [Google Scholar]
