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. 1997 May;179(9):3064–3067. doi: 10.1128/jb.179.9.3064-3067.1997

A novel Arthrobacter beta-galactosidase with homology to eucaryotic beta-galactosidases.

K Gutshall 1, K Wang 1, J E Brenchley 1
PMCID: PMC179077  PMID: 9139931

Abstract

An Arthrobacter beta-galactosidase has homology with the lysosomal acid beta-galactosidases from humans and mice and with a Xanthomonas manihotis enzyme. Phylogenetic analysis of the deduced amino acid sequence showed an unusual pattern, with this procaryotic enzyme clustering within the animal clade. The gene encodes a subunit of 52 kDa, and the enzyme appears to be active as a dimer. The enzyme hydrolyzed substrates with either a beta-1,4 or a beta-1,3 linkage.

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Selected References

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