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. 1989 Feb;64(2):211–213. doi: 10.1136/adc.64.2.211

Acute viral hepatitis: aetiology and evolution.

C B Chow 1, T T Lau 1, N K Leung 1, W K Chang 1
PMCID: PMC1791845  PMID: 2494951

Abstract

Over a period of three and a half years, 348 consecutive children with acute hepatitis were studied. There were 205 boys and 143 girls aged from 3 months to 12 years old. The most common type was hepatitis A, of which there were 281 cases, 81% of the total; there were 41 in the under 4 years old age group (63% of that group), 99 in the 5-8 year old age group (87% of that group) and 141 in the 8-12 year old age group (83% of that group). Hepatitis B occurred in 29 (8% of the total), and non-A, non-B hepatitis occurred in 35 (10%). All the children with hepatitis A and all but one with hepatitis B recovered. There were three deaths from fulminant hepatitis, one in the group with hepatitis B and two with non-A, non-B. Clearance of the hepatitis B surface antigen was fast, by six months 26 patients having cleared the antigen and 21 (77%) being positive for hepatitis B surface antibody. One patient became a carrier of hepatitis B surface antigen.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Caporaso N., Coltorti M., Del Vecchio-Blanco C., Mele A., Ambrogio G., Stroffolini T., Aldershvile J., Nielsen J. O. Acute viral hepatitis in childhood: etiology and evolution. J Pediatr Gastroenterol Nutr. 1983;2(1):99–104. doi: 10.1097/00005176-198302010-00011. [DOI] [PubMed] [Google Scholar]
  2. Frösner G. G., Papaevangelou G., Bütler R., Iwarson S., Lindholm A., Couroucé-Pauty A., Haas H., Deinhardt F. Antibody against hepatitis A in seven European countries. I. Comparison of prevalence data in different age groups. Am J Epidemiol. 1979 Jul;110(1):63–69. doi: 10.1093/oxfordjournals.aje.a112788. [DOI] [PubMed] [Google Scholar]
  3. Gerety R. J., Schweitzer I. L. Viral hepatitis type B during pregnancy, the neonatal period, and infancy. J Pediatr. 1977 Mar;90(3):368–374. doi: 10.1016/s0022-3476(77)80695-1. [DOI] [PubMed] [Google Scholar]
  4. Mowat A. P. Viral hepatitis in infancy and childhood. Clin Gastroenterol. 1980 Jan;9(1):191–212. [PubMed] [Google Scholar]
  5. Tabor E. The three viruses of non-A, non-B hepatitis. Lancet. 1985 Mar 30;1(8431):743–745. doi: 10.1016/s0140-6736(85)91274-7. [DOI] [PubMed] [Google Scholar]
  6. Vittal S. B., Thomas W., Jr, Clowdus B. F. Acute viral hepatitis. Course and incidence of progression to chronic hepatitis. Am J Med. 1973 Dec;55(6):757–761. doi: 10.1016/0002-9343(73)90256-8. [DOI] [PubMed] [Google Scholar]

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