Abstract
Plasma concentrations of vitamin K1 were similar in 37 patients with cystic fibrosis (median 46 ng/l) and 16 controls (49 ng/l). The plasma concentrations were lower than those previously described in adults, but higher than in neonates. There was no association between an increase in prothrombin time and vitamin K1 plasma concentration.
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Selected References
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- Corrigan J. J., Jr, Taussig L. M., Beckerman R., Wagener J. S. Factor II (prothrombin) coagulant activity in immunoreactive protein: detection of vitamin K deficiency and liver disease in patients with cystic fibrosis. J Pediatr. 1981 Aug;99(2):254–257. doi: 10.1016/s0022-3476(81)80468-4. [DOI] [PubMed] [Google Scholar]
- Hart J. P., Shearer M. J., McCarthy P. T., Rahim S. Voltammetric behaviour of phylloquinone (vitamin K1) at a glassy-carbon electrode and determination of the vitamin in plasma using high-performance liquid chromatography with electrochemical detection. Analyst. 1984 Apr;109(4):477–481. doi: 10.1039/an9840900477. [DOI] [PubMed] [Google Scholar]
- Komp D. M., Selden R. F., Jr Coagulation abnormalities in cystic fibrosis. Chest. 1970 Nov;58(5):501–503. doi: 10.1378/chest.58.5.501. [DOI] [PubMed] [Google Scholar]
- Shearer M. J., Rahim S., Barkhan P., Stimmler L. Plasma vitamin K1 in mothers and their newborn babies. Lancet. 1982 Aug 28;2(8296):460–463. doi: 10.1016/s0140-6736(82)90493-7. [DOI] [PubMed] [Google Scholar]
- Torstenson O. L., Humphrey G. B., Edson J. R., Warwick W. J. Cystic fibrosis presenting with severe hemorrhage due to vitamin K malabsorption: a report of three cases. Pediatrics. 1970 May;45(5):857–861. [PubMed] [Google Scholar]