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. 1990 Apr;65(4):448–449. doi: 10.1136/adc.65.4.448

Treatment of constitutional delay of growth and puberty with oxandrolone compared with growth hormone.

A Buyukgebiz 1, P C Hindmarsh 1, C G Brook 1
PMCID: PMC1792201  PMID: 2346341

Abstract

The effects of oxandrolone or biosynthetic human growth hormone (r-hGH) on the growth of 26 boys with constitutional delay of growth and puberty were studied. Both regimens increased growth rate twofold, oxandrolone to a greater extent than r-hGH. We conclude that oxandrolone is a more effective method of increasing growth rate in such children.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bierich J. R. Treatment of constitutional delay of growth and adolescence with human growth hormone. Klin Padiatr. 1983 Sep-Oct;195(5):309–316. doi: 10.1055/s-2008-1034388. [DOI] [PubMed] [Google Scholar]
  2. Clayton P. E., Shalet S. M., Price D. A., Addison G. M. Growth and growth hormone responses to oxandrolone in boys with constitutional delay of growth and puberty (CDGP). Clin Endocrinol (Oxf) 1988 Aug;29(2):123–130. doi: 10.1111/j.1365-2265.1988.tb00254.x. [DOI] [PubMed] [Google Scholar]
  3. Eastman C. J., Lazarus L., Stuart M. C., Casey J. H. The effect of puberty on growth hormone secretion in boys with short stature and delayed adolescence. Aust N Z J Med. 1971 May;1(2):154–159. doi: 10.1111/j.1445-5994.1971.tb02283.x. [DOI] [PubMed] [Google Scholar]
  4. Stanhope R., Brook C. G. Oxandrolone in low dose for constitutional delay of growth and puberty in boys. Arch Dis Child. 1985 Apr;60(4):379–381. doi: 10.1136/adc.60.4.379. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Stanhope R., Buchanan C. R., Fenn G. C., Preece M. A. Double blind placebo controlled trial of low dose oxandrolone in the treatment of boys with constitutional delay of growth and puberty. Arch Dis Child. 1988 May;63(5):501–505. doi: 10.1136/adc.63.5.501. [DOI] [PMC free article] [PubMed] [Google Scholar]

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