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. 1997 Aug;179(15):4959–4961. doi: 10.1128/jb.179.15.4959-4961.1997

A Bacillus subtilis gene encoding a protein similar to nucleotide sugar transferases influences cell shape and viability.

K D Price 1, S Roels 1, R Losick 1
PMCID: PMC179349  PMID: 9244290

Abstract

Bacillus subtilis gene ypfP, which is located at 196 degrees on the genetic map, shows similarity to both the monogalactosyldiacylglycerol synthase gene of Cucumis sativus, which encodes a galactosyltransferase, and the murG genes of B. subtilis, Escherichia coli, Haemophilus influenzae, and Synechocystis sp. strain PCC6803, which encode N-acetylglucosaminyltransferases involved in peptidoglycan biosynthesis. Cells containing a null mutation of ypfP are shorter and rounder than wild-type cells during growth in Luria-Bertani medium and glucose minimal medium. In addition, the mutant cells preferentially undergo lysis when grown on solid Luria-Bertani medium.

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Selected References

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