Abstract
A follow up of a cohort of 736 healthy full term children with exposure to cows' milk based formula and breast milk from donors on the maternity ward was performed. The children were divided into three exposure groups according to the feeding patterns on the maternity ward. Group 1 received only mother's milk, group 2 mother's milk and human donors' milk, and group 3 received mother's milk, donors' milk and cows' milk based formula. The children were investigated at 7 years of age, by examining their medical files, and at 11 and 14 years, by questionnaires regarding symptoms of atopic disease. No significant differences between the three groups at follow up were found in the cumulative incidences of atopic diseases. The amount of formula given did not affect the risk of developing atopic disease. Children with a family history of such diseases ran the same risk of subsequent atopic disease whether they were fed formula or breast milk alone. Cows' milk based formula given on the maternity ward does not seem to increase the risk of developing atopic disease.
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Selected References
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- Aberg N., Engström I., Lindberg U. Allergic diseases in Swedish school children. Acta Paediatr Scand. 1989 Mar;78(2):246–252. doi: 10.1111/j.1651-2227.1989.tb11064.x. [DOI] [PubMed] [Google Scholar]
- Burr M. L. Does infant feeding affect the risk of allergy? Arch Dis Child. 1983 Jul;58(7):561–565. doi: 10.1136/adc.58.7.561. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Delire M., Cambiaso C. L., Masson P. L. Circulating immune complexes in infants fed on cow's milk. Nature. 1978 Apr 13;272(5654):632–632. doi: 10.1038/272632a0. [DOI] [PubMed] [Google Scholar]
- Firer M. A., Hosking C. S., Hill D. J. Effect of antigen load on development of milk antibodies in infants allergic to milk. Br Med J (Clin Res Ed) 1981 Sep 12;283(6293):693–696. doi: 10.1136/bmj.283.6293.693. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hanson L. A., Ahlstedt S., Andersson B., Carlsson B., Fällström S. P., Mellander L., Porras O., Söderström T., Edén C. S. Protective factors in milk and the development of the immune system. Pediatrics. 1985 Jan;75(1 Pt 2):172–176. [PubMed] [Google Scholar]
- Hattevig G., Kjellman B., Björkstén B., Johansson S. G. The prevalence of allergy and IgE antibodies to inhalant allergens in Swedish school children. Acta Paediatr Scand. 1987 Mar;76(2):349–355. doi: 10.1111/j.1651-2227.1987.tb10473.x. [DOI] [PubMed] [Google Scholar]
- Høst A., Husby S., Osterballe O. A prospective study of cow's milk allergy in exclusively breast-fed infants. Incidence, pathogenetic role of early inadvertent exposure to cow's milk formula, and characterization of bovine milk protein in human milk. Acta Paediatr Scand. 1988 Sep;77(5):663–670. doi: 10.1111/j.1651-2227.1988.tb10727.x. [DOI] [PubMed] [Google Scholar]
- Jarrett E. E. Activation of IgE regulatory mechanisms by transmucosal absorption of antigen. Lancet. 1977 Jul 30;2(8031):223–225. doi: 10.1016/s0140-6736(77)92837-9. [DOI] [PubMed] [Google Scholar]
- Kjellman N. I., Croner S. Cord blood IgE determination for allergy prediction--a follow-up to seven years of age in 1,651 children. Ann Allergy. 1984 Aug;53(2):167–171. [PubMed] [Google Scholar]
- Kramer M. S. Does breast feeding help protect against atopic disease? Biology, methodology, and a golden jubilee of controversy. J Pediatr. 1988 Feb;112(2):181–190. doi: 10.1016/s0022-3476(88)80054-4. [DOI] [PubMed] [Google Scholar]
- Lindfors A., Enocksson E. Development of atopic disease after early administration of cow milk formula. Allergy. 1988 Jan;43(1):11–16. doi: 10.1111/j.1398-9995.1988.tb02038.x. [DOI] [PubMed] [Google Scholar]
- Stintzing G., Zetterström R. Cow's milk allergy, incidence and pathogenetic role of early exposure to cow's milk formula. Acta Paediatr Scand. 1979 May;68(3):383–387. doi: 10.1111/j.1651-2227.1979.tb05024.x. [DOI] [PubMed] [Google Scholar]