Abstract
The peripheral blood mononuclear cell subsets in patients with Kawasaki disease and coronary artery lesions were investigated. Of the 106 patients 14 had lesions. Patients with Kawasaki disease and coronary artery lesions were found to have increased counts of CD14+ macrophages/monocytes compared with those of patients with Kawasaki disease without lesions. The absolute counts of CD14+ macrophages/monocytes form an important parameter to determine the severity of vascular damage during acute Kawasaki disease.
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Selected References
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- Furukawa S., Matsubara T., Motohashi T., Nakachi S., Sasai K., Yabuta K. Expression of Fc epsilon R2/CD23 on peripheral blood macrophages/monocytes in Kawasaki disease. Clin Immunol Immunopathol. 1990 Aug;56(2):280–286. doi: 10.1016/0090-1229(90)90149-k. [DOI] [PubMed] [Google Scholar]
- Furukawa S., Matsubara T., Tsuji K., Motohashi T., Okumura K., Yabuta K. Serum soluble CD4 and CD8 levels in Kawasaki disease. Clin Exp Immunol. 1991 Oct;86(1):134–139. doi: 10.1111/j.1365-2249.1991.tb05785.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Furukawa S., Matsubara T., Yone K., Hirano Y., Okumura K., Yabuta K. Kawasaki disease differs from anaphylactoid purpura and measles with regard to tumour necrosis factor-alpha and interleukin 6 in serum. Eur J Pediatr. 1992 Jan;151(1):44–47. doi: 10.1007/BF02073890. [DOI] [PubMed] [Google Scholar]
- Furusho K., Kamiya T., Nakano H., Kiyosawa N., Shinomiya K., Hayashidera T., Tamura T., Hirose O., Manabe Y., Yokoyama T. High-dose intravenous gammaglobulin for Kawasaki disease. Lancet. 1984 Nov 10;2(8411):1055–1058. doi: 10.1016/s0140-6736(84)91504-6. [DOI] [PubMed] [Google Scholar]
- Leung D. Y., Burns J. C., Newburger J. W., Geha R. S. Reversal of lymphocyte activation in vivo in the Kawasaki syndrome by intravenous gammaglobulin. J Clin Invest. 1987 Feb;79(2):468–472. doi: 10.1172/JCI112835. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Leung D. Y., Cotran R. S., Kurt-Jones E., Burns J. C., Newburger J. W., Pober J. S. Endothelial cell activation and high interleukin-1 secretion in the pathogenesis of acute Kawasaki disease. Lancet. 1989 Dec 2;2(8675):1298–1302. doi: 10.1016/s0140-6736(89)91910-7. [DOI] [PubMed] [Google Scholar]
- Matsubara T., Furukawa S., Yabuta K. Serum levels of tumor necrosis factor, interleukin 2 receptor, and interferon-gamma in Kawasaki disease involved coronary-artery lesions. Clin Immunol Immunopathol. 1990 Jul;56(1):29–36. doi: 10.1016/0090-1229(90)90166-n. [DOI] [PubMed] [Google Scholar]