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. 1971 Feb 6;1(5744):324–326. doi: 10.1136/bmj.1.5744.324

Importance of Central Vasomotor Effects in Angiotensin-induced Hypertension

G C Scroop, Frances Katic, M D Joy, R D Lowe
PMCID: PMC1794907  PMID: 4322433

Abstract

Ablation of the areas postrema in 10 dogs caused a highly significant reduction in the pressor response to intravenous infusions of angiotensin yet was without significant effect on the pressor response to intravenous infusions of noradrenaline. The reduction in the pressor response to angiotensin is almost certainly due to abolition of the specific central autonomic effects of the hormone which are dependent on the integrity of the areas postrema. It is suggested that this central effect also contributes to the cardiovascular response to endogenous angiotensin.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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