Skip to main content
British Medical Journal logoLink to British Medical Journal
. 1971 Oct 23;4(5781):204–206. doi: 10.1136/bmj.4.5781.204

Hyposensitization with Dermatophagoides pteronyssinus Antigen: Trial in Asthma Induced by House Dust

A P Smith
PMCID: PMC1799252  PMID: 4940158

Abstract

A double-blind clinical trial of hyposensitization with aqueous extracts of Dermatophagoides pteronyssinus (the house-dust mite) and human skin scales showed a substantial improvement in symptoms in 11 asthmatics allergic to house dust treated with the D. pteronyssinus extract and a reduction in their need for other therapy. Five patients were well for a year but six relapsed. These results contrasted with the generally unfavourable course of the patients treated with the extract of human skin scales. Asthma due to house-dust allergy may be substantially improved by hyposensitization with D. pteronyssinus extract.

Full text

PDF
204

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Brown H. M., Filer J. L. Role of mites in allergy to house dust. Br Med J. 1968 Sep 14;3(5619):646–647. doi: 10.1136/bmj.3.5619.646. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Maunsell K., Wraith D. G., Cunnington A. M. Mites and house-dust allergy in bronchial asthma. Lancet. 1968 Jun 15;1(7555):1267–1270. doi: 10.1016/s0140-6736(68)92289-7. [DOI] [PubMed] [Google Scholar]
  3. McAllen M. K., Assem E. S., Maunsell K. House-dust mite asthma. Results of challenge tests on five criteria with Dermatophagoides pteronyssinus. Br Med J. 1970 May 30;2(5708):501–504. doi: 10.1136/bmj.2.5708.501. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Pepys J., Chan M., Hargreave F. E. Mites and house-dust allergy. Lancet. 1968 Jun 15;1(7555):1270–1272. doi: 10.1016/s0140-6736(68)92290-3. [DOI] [PubMed] [Google Scholar]

Articles from British Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES