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. 1984 Jul;26(1):115–116. doi: 10.1128/aac.26.1.115

Penetration of ceftazidime into the cerebrospinal fluid of patients with and without evidence of meningeal inflammation.

I W Fong, K B Tomkins
PMCID: PMC179932  PMID: 6383206

Abstract

The concentrations of ceftazidime in the serum and cerebrospinal fluid of patients with and without meningitis were measured at various times after a 2- or 3-g dose. At similar concentrations in serum, ceftazidime concentrations in cerebrospinal fluid at a given time were substantially lower in patients without meningitis (mean, 0.8 micrograms/ml) than in those with meningitis (mean, 22.6 micrograms/ml).

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Barling R. W., Selkon J. B. The penetration of antibiotics into cerebrospinal fluid and brain tissue. J Antimicrob Chemother. 1978 May;4(3):203–227. doi: 10.1093/jac/4.3.203. [DOI] [PubMed] [Google Scholar]
  2. Modai J., Vittecoq D., Decazes J. M., Wolff M., Meulemans A. Penetration of ceftazidime into cerebrospinal fluid of patients with bacterial meningitis. Antimicrob Agents Chemother. 1983 Jul;24(1):126–128. doi: 10.1128/aac.24.1.126. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Myers C. M., Blumer J. L. Determination of ceftazidime in biological fluids by using high-pressure liquid chromatography. Antimicrob Agents Chemother. 1983 Sep;24(3):343–346. doi: 10.1128/aac.24.3.343. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Norrby S. R. Ceftazidime in clinical practice - a summary. J Antimicrob Chemother. 1983 Jul;12 (Suppl A):405–408. doi: 10.1093/jac/12.suppl_a.405. [DOI] [PubMed] [Google Scholar]

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