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British Medical Journal logoLink to British Medical Journal
. 1971 Jul 10;3(5766):84–86.

Betamethasone 17-Valerate and Prednisolone 21-Phosphate Retention Enemata in Proctocolitis: A MULTICENTRE TRIAL

PMCID: PMC1800163  PMID: 5090826

Abstract

The efficacy of betamethasone 17-valerate (5 mg) and prednisolone 21-phosphate (20 mg) retention enemata in the outpatient treatment of distal proctocolitis was compared in a formal clinical trial. The two treatments were equally effective in inducing remissions of the disease, but the betamethasone valerate enema produced less adrenal suppression.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BARON J. H., CONNELL A. M., LENNARD-JONES J. E. VARIATION BETWEEN OBSERVERS IN DESCRIBING MUCOSAL APPEARANCES IN PROCTOCOLITIS. Br Med J. 1964 Jan 11;1(5375):89–92. doi: 10.1136/bmj.1.5375.89. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BLACK S., FRIEDMAN M. ADRENAL FUNCTION AND THE INHIBITION OF ALLERGIC RESPONSES UNDER HYPNOSIS. Br Med J. 1965 Feb 27;1(5434):562–567. doi: 10.1136/bmj.1.5434.562. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. LENNARD-JONES J. E., BARON J. H., CONNELL A. M., JONES F. A. A double blind controlled trial of prednisolone-21-phosphate suppositories in the treatment of idiopathic proctitis. Gut. 1962 Sep;3:207–210. doi: 10.1136/gut.3.3.207. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. MATTS S. G. Betamethasone enemata in ulcerative colitis. Gut. 1962 Dec;3:312–314. doi: 10.1136/gut.3.4.312. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Munro D. D., Wilson H. T., Rhodes E. L. Comparison of betamethasone 17-valerate ointment with fluocortolone and fluocortolone caproate ointment. Br Med J. 1967 Nov 4;4(5574):275–276. doi: 10.1136/bmj.4.5574.275. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. TRUELOVE S. C., HAMBLING M. H. Treatment of ulcerative colitis with local hydrocortisone hemisuccinate sodium; a report on a controlled therapeutic trial. Br Med J. 1958 Nov 1;2(5104):1072–1077. doi: 10.1136/bmj.2.5104.1072. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. WILLIAMS D. I., WILKINSON D. S., OVERTON J., MILNE J. A., MCKENNA W. B., LYELL A., CHURCH R. BETAMETHASONE 17-VALERATE: A NEW TOPICAL CORTICOSTEROID. Lancet. 1964 May 30;1(7344):1177–1179. doi: 10.1016/s0140-6736(64)91205-x. [DOI] [PubMed] [Google Scholar]
  8. WOOD W. A., WALTERS G., FLAVELLMATTS S. G. URINARY EXCRETION OF PREDNISOLONE AFTER INTRARECTAL THERAPY IN ULCERATIVE COLITIS. Br Med J. 1964 Oct 24;2(5416):1045–1046. doi: 10.1136/bmj.2.5416.1045. [DOI] [PMC free article] [PubMed] [Google Scholar]

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