Abstract
A Kveim suspension has been shown to inhibit the migration of leucocytes in vitro from 12 out of 18 patients with Crohn's disease but to have no comparable effect on leucocytes from patients with ulcerative colitis or from a group of patients with other diseases. These findings provide further evidence of cross-reactivity or of a possible aetiological link between Crohn's disease and sarcoidosis and suggest a further immunological distinction between Crohn's disease and ulcerative colitis.
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Selected References
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- Bendixen G., Soborg M. A leucocyte migration technique for in vitro detection of cellular (delayed type) hypersensitivity in man. Dan Med Bull. 1969 Jan;16(1):1–6. [PubMed] [Google Scholar]
- Bendixen G. Specific inhibition of the in vitro migration of leucocytes in ulcerative colitis and Crohn's disease. Scand J Gastroenterol. 1967;2(3):214–221. doi: 10.3109/00365526709180072. [DOI] [PubMed] [Google Scholar]
- Dykes P. W. Delayed hypersensitivity in Crohn's disease. Proc R Soc Med. 1970 Sep;63(9):906–908. [PMC free article] [PubMed] [Google Scholar]
- Glotzer D. J., Gardner R. C., Goldman H., Hinrichs H. R., Rosen H., Zetzel L. Comparative features and course of ulcerative and granulomatous colitis. N Engl J Med. 1970 Mar 12;282(11):582–587. doi: 10.1056/NEJM197003122821102. [DOI] [PubMed] [Google Scholar]
- Hardt F., Wanstrup J. Sarcoidosis. An in vitro Kveim reaction based on the leucocyte migration test. Acta Pathol Microbiol Scand. 1969;76(3):493–494. doi: 10.1111/j.1699-0463.1969.tb03279.x. [DOI] [PubMed] [Google Scholar]
- Hart P. D., Rees R. J. Lepromin and Kveim antigen reactivity in man, and their relation to tuberculin reactivity. Br Med Bull. 1967 Jan;23(1):80–85. doi: 10.1093/oxfordjournals.bmb.a070522. [DOI] [PubMed] [Google Scholar]
- LOCKHART-MUMMERY H. E., MORSON B. C. CROHN'S DISEASE OF THE LARGE INTESTINE. Gut. 1964 Dec;5:493–509. doi: 10.1136/gut.5.6.493. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Marshak R. H., Lindner A. E. Ulcerative and granulomatous colitis. J Mt Sinai Hosp N Y. 1966 Nov-Dec;33(6):444–502. [PubMed] [Google Scholar]
- Mitchell D. N., Cannon P., Dyer N. H., Hinson K. F., Willoughby J. M. Further observations on Kveim test in Crohn's disease. Lancet. 1970 Sep 5;2(7671):496–498. doi: 10.1016/s0140-6736(70)90114-5. [DOI] [PubMed] [Google Scholar]
- Mitchell D. N., Cannon P., Dyer N. H., Hinson K. F., Willoughby J. M. The Kveim test in Crohn's disease. Lancet. 1969 Sep 13;2(7620):571–573. doi: 10.1016/s0140-6736(69)90265-7. [DOI] [PubMed] [Google Scholar]
- Monk M., Mendeloff A. I., Siegel C. I., Lilienfeld A. An epidemiological study of ulcerative colitis and regional enteritis among adults in Baltimore. II. Social and demographic factors. Gastroenterology. 1969 May;56(5):847–857. [PubMed] [Google Scholar]
- Schachter H., Goldstein M. J., Rappaport H., Fennessy J. J., Kirsner J. B. Ulcerative and "granulomatous" colitis--validity of differential diagnostic criteria. A study of 100 patients treated by total colectomy. Ann Intern Med. 1970 Jun;72(6):841–851. doi: 10.7326/0003-4819-72-6-841. [DOI] [PubMed] [Google Scholar]
- Shorter R. G., Cardoza M. R., ReMine S. G., Spencer R. J., Huizenga K. A. Modification of in vitro cytotoxicity of lymphocytes from patients with chronic ulcerative colitis or granulomatous colitis for allogenic colonic epithelial cells. Gastroenterology. 1970 May;58(5):692–698. [PubMed] [Google Scholar]
- Soborg M., Bendixen G. Human lymphocyte migration as a parameter of hypersensitivity. Acta Med Scand. 1967 Feb;181(2):247–256. doi: 10.1111/j.0954-6820.1967.tb07255.x. [DOI] [PubMed] [Google Scholar]
- Van der Reis L. Ulcerative colitis and granulomatous disease of the bowel. Some of their familial and genetic characteristics with a report of ulcerative colitis in three of five siblings. Am J Gastroenterol. 1969 Jul;52(1):56–64. [PubMed] [Google Scholar]