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. 1985 Apr;27(4):650–651. doi: 10.1128/aac.27.4.650

Inhibitory effect of cephalosporins on gamma-aminobutyric acid receptor binding in rat synaptic membranes.

S Hori, S Kurioka, M Matsuda, J Shimada
PMCID: PMC180115  PMID: 2988433

Abstract

Cephalosporins inhibited gamma-aminobutyric acid receptor binding in a concentration-dependent manner in vitro. Scatchard analysis revealed that cefazolin decreased the binding capacity but did not change the affinity of the receptor. It is suggested that this inhibition of gamma-aminobutyric acid receptor binding may be involved in the induction of convulsions by cephalosporins.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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