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. 1985 Jun;27(6):921–924. doi: 10.1128/aac.27.6.921

Alteration of ribosomes and RNA polymerase in drug-resistant clinical isolates of Mycobacterium tuberculosis.

T Yamada, A Nagata, Y Ono, Y Suzuki, T Yamanouchi
PMCID: PMC180187  PMID: 3927838

Abstract

The biochemical mechanism of resistance to kanamycin, viomycin, and rifampin in five clinical isolates of Mycobacterium tuberculosis was studied. Resistance to viomycin and kanamycin was attributed to altered ribosomes, whereas resistance to rifampin was attributed to an alteration of RNA polymerase. Ribosomal resistance was, however, not the only way of expressing resistance to viomycin and kanamycin.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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