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. 1985 Dec;28(6):807–811. doi: 10.1128/aac.28.6.807

Antimicrobial susceptibility of five subgroups of Mycobacterium fortuitum and Mycobacterium chelonae.

J M Swenson, R J Wallace Jr, V A Silcox, C Thornsberry
PMCID: PMC180333  PMID: 4083863

Abstract

Broth microdilution MICs were determined for 258 clinical isolates of Mycobacterium fortuitum (3 biovariants) and M. chelonae (2 subspecies) with amikacin, tobramycin, cefoxitin, doxycycline, erythromycin, and sulfamethoxazole-trimethoprim and with several new beta-lactams and aminoglycosides and ciprofloxacin. Variations in susceptibility by and within species subgroups confirm the need for susceptibility testing against clinically important strains.

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Selected References

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  1. Casal M. J., Rodriguez F. C. In vitro susceptibility of Mycobacterium fortuitum and M. chelonei to sisomicin, gentamicin and tobramycin. Ann Microbiol (Paris) 1983 Nov-Dec;134B(3):451–454. [PubMed] [Google Scholar]
  2. Casal M., Rodríguez F. In vitro susceptibility of mycobacterium fortuitum and mycobacterium chelonei to cefoxitin. Tubercle. 1982 Jun;63(2):125–127. doi: 10.1016/s0041-3879(82)80049-4. [DOI] [PubMed] [Google Scholar]
  3. Cynamon M. H., Palmer G. S. In vitro susceptibility of Mycobacterium fortuitum to N-formimidoyl thienamycin and several cephamycins. Antimicrob Agents Chemother. 1982 Dec;22(6):1079–1081. doi: 10.1128/aac.22.6.1079. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Cynamon M. H., Palmer G. S. In vitro susceptibility of Mycobacterium fortuitum to amoxicillin or cephalothin in combination with clavulanic acid. Antimicrob Agents Chemother. 1983 Jun;23(6):935–937. doi: 10.1128/aac.23.6.935. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Dalovisio J. R., Pankey G. A. In vitro susceptiiblity of Mycobacterium fortuitum and Mycobacterium chelonei to amikacin. J Infect Dis. 1978 Mar;137(3):318–321. doi: 10.1093/infdis/137.3.318. [DOI] [PubMed] [Google Scholar]
  6. Dalovisio J. R., Pankey G. A. Problems in diagnosis and therapy of Mycobacterium fortuitum infections. Am Rev Respir Dis. 1978 Apr;117(4):625–630. doi: 10.1164/arrd.1978.117.4.625. [DOI] [PubMed] [Google Scholar]
  7. Dalovisio J. R., Pankey G. A., Wallace R. J., Jones D. B. Clinical usefulness of amikacin and doxycycline in the treatment of infection due to Mycobacterium fortuitum and Mycobacterium chelonei. Rev Infect Dis. 1981 Sep-Oct;3(5):1068–1074. doi: 10.1093/clinids/3.5.1068. [DOI] [PubMed] [Google Scholar]
  8. Garcia-Rodriguez J. A., Martin-Luengo F. Activity of amikacin, erythromycin and doxycyline against Mycobacterium chelonei and Mycobacterium fortuitum. Tubercle. 1978 Dec;59(4):277–280. doi: 10.1016/0041-3879(78)90005-3. [DOI] [PubMed] [Google Scholar]
  9. Lévy-Frébault V., Daffé M., Goh K. S., Lanéelle M. A., Asselineau C., David H. L. Identification of Mycobacterium fortuitum and Mycobacterium chelonei. J Clin Microbiol. 1983 May;17(5):744–752. doi: 10.1128/jcm.17.5.744-752.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. McClatchy J. K., Waggoner R. F., Lester W. In vitro susceptibility of mycobacteria to rifampin. Am Rev Respir Dis. 1969 Aug;100(2):234–236. doi: 10.1164/arrd.1969.100.2.234. [DOI] [PubMed] [Google Scholar]
  11. Sanders W. E., Cacciatore R., Valdez H., Pejovic I., Dunbar F. P. Activity of gentamicin against mycobacteria in vitro and against Mycobacterium tuberculosis in mice. J Infect Dis. 1971 Dec;124 (Suppl):S33–S36. doi: 10.1093/infdis/124.supplement_1.s33. [DOI] [PubMed] [Google Scholar]
  12. Sanders W. E., Jr, Hartwig E. C., Schneider N. J., Cacciatore R., Valdez H. Susceptibility of organisms in the Mycobacterium fortuitum complex to antituberculous and other antimicrobial agents. Antimicrob Agents Chemother. 1977 Aug;12(2):295–297. doi: 10.1128/aac.12.2.295. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Silcox V. A., Good R. C., Floyd M. M. Identification of clinically significant Mycobacterium fortuitum complex isolates. J Clin Microbiol. 1981 Dec;14(6):686–691. doi: 10.1128/jcm.14.6.686-691.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Stone M. S., Wallace R. J., Jr, Swenson J. M., Thornsberry C., Christensen L. A. Agar disk elution method for susceptibility testing of Mycobacterium marinum and Mycobacterium fortuitum complex to sulfonamides and antibiotics. Antimicrob Agents Chemother. 1983 Oct;24(4):486–493. doi: 10.1128/aac.24.4.486. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Swenson J. M., Thornsberry C., Silcox V. A. Rapidly growing mycobacteria: testing of susceptibility to 34 antimicrobial agents by broth microdilution. Antimicrob Agents Chemother. 1982 Aug;22(2):186–192. doi: 10.1128/aac.22.2.186. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Wallace R. J., Jr, Dalovisio J. R., Pankey G. A. Disk diffusion testing of susceptibility of Mycobacterium fortuitum and Mycobacterium chelonei to antibacterial agents. Antimicrob Agents Chemother. 1979 Nov;16(5):611–614. doi: 10.1128/aac.16.5.611. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Wallace R. J., Jr, Jones D. B., Wiss K. Sulfonamide activity against Mycobacterium fortuitum and Mycobacterium chelonei. Rev Infect Dis. 1981 Sep-Oct;3(5):898–904. doi: 10.1093/clinids/3.5.898. [DOI] [PubMed] [Google Scholar]
  18. Wallace R. J., Jr, Swenson J. M., Silcox V. A., Bullen M. G. Treatment of nonpulmonary infections due to Mycobacterium fortuitum and Mycobacterium chelonei on the basis of in vitro susceptibilities. J Infect Dis. 1985 Sep;152(3):500–514. doi: 10.1093/infdis/152.3.500. [DOI] [PubMed] [Google Scholar]
  19. Wallace R. J., Jr, Swenson J. M., Silcox V. A., Good R. C., Tschen J. A., Stone M. S. Spectrum of disease due to rapidly growing mycobacteria. Rev Infect Dis. 1983 Jul-Aug;5(4):657–679. doi: 10.1093/clinids/5.4.657. [DOI] [PubMed] [Google Scholar]
  20. Wallace R. J., Jr, Wiss K., Bushby M. B., Hollowell D. C. In vitro activity of trimethoprim and sulfamethoxazole against the nontuberculous mycobacteria. Rev Infect Dis. 1982 Mar-Apr;4(2):326–331. doi: 10.1093/clinids/4.2.326. [DOI] [PubMed] [Google Scholar]
  21. Welch D. F., Kelly M. T. Antimicrobial susceptibility testing of Mycobacterium fortuitum complex. Antimicrob Agents Chemother. 1979 Jun;15(6):754–757. doi: 10.1128/aac.15.6.754. [DOI] [PMC free article] [PubMed] [Google Scholar]

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