Abstract
The in vitro activity of teicoplanin was compared with that of vancomycin against fecal isolates of Clostridium difficile. All strains were susceptible to both antibiotics, but teicoplanin was fourfold more active than vancomycin. Cholestyramine was found to bind teicoplanin almost completely, reducing its activity to nondetectable levels.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bardone M. R., Paternoster M., Coronelli C. Teichomycins, new antibiotics from Actinoplanes teichomyceticus nov. sp. II. Extraction and chemical characterization. J Antibiot (Tokyo) 1978 Mar;31(3):170–177. doi: 10.7164/antibiotics.31.170. [DOI] [PubMed] [Google Scholar]
- George R. H., Youngs D. J., Johnson E. M., Burdon D. W. Anion-exchange resins in pseudomembranous colitis. Lancet. 1978 Sep 16;2(8090):624–624. doi: 10.1016/s0140-6736(78)92840-4. [DOI] [PubMed] [Google Scholar]
- Glupczynski Y., Labbe M., Crokaert F., Yourassowsky E. In vitro activity of teicoplanin and vancomycin against anaerobes. Eur J Clin Microbiol. 1984 Feb;3(1):50–51. doi: 10.1007/BF02032822. [DOI] [PubMed] [Google Scholar]
- King C. Y., Barriere S. L. Analysis of the in vitro interaction between vancomycin and cholestyramine. Antimicrob Agents Chemother. 1981 Feb;19(2):326–327. doi: 10.1128/aac.19.2.326. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Silva J., Jr, Batts D. H., Fekety R., Plouffe J. F., Rifkin G. D., Baird I. Treatment of Clostridium difficile colitis and diarrhea with vancomycin. Am J Med. 1981 Nov;71(5):815–822. doi: 10.1016/0002-9343(81)90369-7. [DOI] [PubMed] [Google Scholar]
- Taylor N. S., Bartlett J. G. Binding of Clostridium difficile cytotoxin and vancomycin by anion-exchange resins. J Infect Dis. 1980 Jan;141(1):92–97. doi: 10.1093/infdis/141.1.92. [DOI] [PubMed] [Google Scholar]
- Tedesco F., Markham R., Gurwith M., Christie D., Bartlett J. G. Oral vancomycin for antibiotic-associated pseudomembranous colitis. Lancet. 1978 Jul 29;2(8083):226–228. doi: 10.1016/s0140-6736(78)91741-5. [DOI] [PubMed] [Google Scholar]
- Tuazon C. U., Miller H. Comparative in vitro activities of teichomycin and vancomycin alone and in combination with rifampin and aminoglycosides against staphylococci and enterococci. Antimicrob Agents Chemother. 1984 Apr;25(4):411–412. doi: 10.1128/aac.25.4.411. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Varaldo P. E., Debbia E., Schito G. C. In vitro activity of teichomycin and vancomycin alone and in combination with rifampin. Antimicrob Agents Chemother. 1983 Mar;23(3):402–406. doi: 10.1128/aac.23.3.402. [DOI] [PMC free article] [PubMed] [Google Scholar]