Abstract
An inhibitor which is active against influenza A virus was found in Neuramide, a complex tissue extract that is used as an anti-herpes zoster virus treatment. Kinetic studies showed that significant inhibition of virus production occurred when the inhibitor was added to infected cultures up to 5 h after virus penetration. Molecular sieving fractionation showed that the antiviral activity was contained in a low-molecular-weight fraction (molecular weight, less than 1,000).
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Albrecht T., Zucca M., Dianzani F. Studio su un inibitore della replicazione del virus della varicella-zoster. G Ital Chemioter. 1980 Jul-Dec;27(2):103–106. [PubMed] [Google Scholar]
- Baron S., McKerlie L. Broadly active inhibitor of viruses spontaneously produced by many cell types in culture. Infect Immun. 1981 May;32(2):449–453. doi: 10.1128/iai.32.2.449-453.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Coppenhaver D. H., Baron J. L., McKerlie M. L., Sabados J., Baron S. Size and stability of a naturally occurring virus inhibitor. Antimicrob Agents Chemother. 1984 May;25(5):646–649. doi: 10.1128/aac.25.5.646. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kumar S., Baron S. Non-interferon cellular products capable of virus inhibition. Tex Rep Biol Med. 1981;41:395–401. [PubMed] [Google Scholar]
- Kumar S., McKerlie M. L., Albrecht T. B., Goldman A. S., Baron S. A broadly active viral inhibitor in human and animal organ extracts and body fluids. Proc Soc Exp Biol Med. 1984 Oct;177(1):104–111. doi: 10.3181/00379727-177-41918. [DOI] [PubMed] [Google Scholar]