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. 1986 Jun;29(6):1095–1097. doi: 10.1128/aac.29.6.1095

Previously undescribed 6.6-kilobase R plasmid in penicillinase-producing Neisseria gonorrhoeae.

A Gouby, G Bourg, M Ramuz
PMCID: PMC180507  PMID: 3089144

Abstract

A penicillin-resistant Neisseria gonorrhoeae strain was isolated. The resistance was due to the production of TEM-1 beta-lactamase encoded by a plasmid. This 6.6-kilobase plasmid was compared with the previously known 7.4- and 5.3-kilobase penicillin R plasmids of N. gonorrhoeae.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Dickgiesser N., Bennett P. M., Richmond M. H. Penicillinase-producing Neisseria gonorrhoeae: a molecular comparison of 5.3-kb and 7.4-kb beta-lactamase plasmids. J Bacteriol. 1982 Sep;151(3):1171–1175. doi: 10.1128/jb.151.3.1171-1175.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Elwell L. P., Roberts M., Mayer L. W., Falkow S. Plasmid-mediated beta-lactamase production in Neisseria gonorrhoeae. Antimicrob Agents Chemother. 1977 Mar;11(3):528–533. doi: 10.1128/aac.11.3.528. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Eriquez L. A., D'Amato R. F. Purification by affinity chromatography and properties of a beta-lactamase isolated from Neisseria gonorrhoeae. Antimicrob Agents Chemother. 1979 Feb;15(2):229–234. doi: 10.1128/aac.15.2.229. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Foster T. J. Plasmid-determined resistance to antimicrobial drugs and toxic metal ions in bacteria. Microbiol Rev. 1983 Sep;47(3):361–409. doi: 10.1128/mr.47.3.361-409.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Labidi A., martin P. M., Guibourdenche M., Riou J. Y. Surveillance épidémiologique des gonocoques producteurs de bêta-lactamase. II--Caractérisation des plasmides de 66 souches isol7es en France (mai 1979 - mars 1983). Pathol Biol (Paris) 1984 Dec;32(10):1013–1018. [PubMed] [Google Scholar]
  6. Lefèvre J. C., Prère M. F., Bouvier F. Isolement et caractérisation d'un plasmide de résistance à la pénicilline, dans une souche de Neisseria gonorrhoeae. Ann Microbiol (Paris) 1981 May-Jun;132(3):283–292. [PubMed] [Google Scholar]
  7. Mathew A., Harris A. M., Marshall M. J., Ross G. W. The use of analytical isoelectric focusing for detection and identification of beta-lactamases. J Gen Microbiol. 1975 May;88(1):169–178. doi: 10.1099/00221287-88-1-169. [DOI] [PubMed] [Google Scholar]
  8. Mayer L. W., Robbins K. E. Evolutionary analysis of the 7.1-kb beta-lactamase-specifying R-plasmid of Neisseria gonorrhoeae by restriction endonucleases. J Bacteriol. 1983 Jun;154(3):1498–1501. doi: 10.1128/jb.154.3.1498-1501.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. McNicol P. J., Albritton W. L., Ronald A. R. Characterization of ampicillin resistance plasmids of Haemophilus ducreyi and Neisseria gonorrhoeae with regard to location of origin of transfer and mobilization by a conjugative plasmid of Haemophilus ducreyi. J Bacteriol. 1983 Oct;156(1):437–440. doi: 10.1128/jb.156.1.437-440.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Norlander L., Davies J. K., Hagblom P., Normark S. Deoxyribonucleic acid modifications and restriction endonuclease production in Neisseria gonorrhoeae. J Bacteriol. 1981 Feb;145(2):788–795. doi: 10.1128/jb.145.2.788-795.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. O'Callaghan C. H., Morris A., Kirby S. M., Shingler A. H. Novel method for detection of beta-lactamases by using a chromogenic cephalosporin substrate. Antimicrob Agents Chemother. 1972 Apr;1(4):283–288. doi: 10.1128/aac.1.4.283. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Perine P. L., Thornsberry C., Schalla W., Biddle J., Siegel M. S., Wong K. H., Thompson S. E. Evidence for two distinct types of penicillinase-producing Neisseria gonorrhoeae. Lancet. 1977 Nov 12;2(8046):993–995. doi: 10.1016/s0140-6736(77)92891-4. [DOI] [PubMed] [Google Scholar]
  13. Phillips I. Beta-lactamase-producing, penicillin-resistant gonococcus. Lancet. 1976 Sep 25;2(7987):656–657. doi: 10.1016/s0140-6736(76)92466-1. [DOI] [PubMed] [Google Scholar]
  14. Roberts M., Elwell L. P., Falkow S. Molecular characterization of two beta-lactamase-specifying plasmids isolated from Neisseria gonorrhoeae. J Bacteriol. 1977 Aug;131(2):557–563. doi: 10.1128/jb.131.2.557-563.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Samuni A. A direct spectrophotometric assay and determination of Michaelis constants for the beta-lactamase reaction. Anal Biochem. 1975 Jan;63(1):17–26. doi: 10.1016/0003-2697(75)90185-2. [DOI] [PubMed] [Google Scholar]
  16. Southern E. M. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol. 1975 Nov 5;98(3):503–517. doi: 10.1016/s0022-2836(75)80083-0. [DOI] [PubMed] [Google Scholar]
  17. Van Embden J. D., Dessens-Kroon M., Van Klingeren B. A new beta-lactamase plasmid in Neisseria gonorrhoeae. J Antimicrob Chemother. 1985 Feb;15(2):247–250. doi: 10.1093/jac/15.2.247. [DOI] [PubMed] [Google Scholar]
  18. van Embden J. D., van Klingeren B., Dessens-Kroon M., van Wijngaarden L. J. Penicillinase-producing Neisseria gonorrhoeae in the Netherlands: epidemiology and genetic and molecular characterization of their plasmids. Antimicrob Agents Chemother. 1980 Nov;18(5):789–797. doi: 10.1128/aac.18.5.789. [DOI] [PMC free article] [PubMed] [Google Scholar]

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