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. 1986 Aug;30(2):211–214. doi: 10.1128/aac.30.2.211

Imipenem-cilastatin as initial therapy for febrile cancer patients.

G P Bodey, M E Alvarez, P G Jones, K V Rolston, L Steelhammer, V Fainstein
PMCID: PMC180520  PMID: 3532942

Abstract

Imipenem-cilastatin was used to treat 79 febrile episodes in 71 cancer patients, most of whom had neutropenia. The overall response rate was 67%, and 76% of the 45 documented infections responded. The response rates for septicemias and pneumonias were 79 and 62%, respectively. Only 1 of the 17 infections caused by gram-negative bacilli failed to respond to this therapy. The most common side effects were skin rash, nausea, and diarrhea. Eight superinfections were detected during therapy.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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