Retraction for Ma and Chang, Structure of the multidrug resistance efflux transporter EmrE from Escherichia coli

BIOPHYSICS. For the article “Structure of the multidrug resistance efflux transporter EmrE from Escherichia coli,” by Che Ma and Geoffrey Chang, which appeared in issue 9, March 2, 2004, of Proc Natl Acad Sci USA (101:2852–2857; first published February 17, 2004; 10.1073/pnas.0400137101), the authors wish to note the following: “We have recently discovered that the structure was determined in the incorrect hand. An in-house data reduction program introduced a change in sign for anomalous differences. This program, which was not part of a conventional data processing package, converted the anomalous pairs (I+ and I−) to (F− and F+), thereby introducing a sign change that resulted in the structure being reported in the wrong hand. The Protein Data Bank file (PDB ID code 1S7B) has been moved to the archive of obsolete PDB entries. The structures will be recalculated from the original data, using the proper sign for the anomalous differences, and the new Cα coordinates and structure factors will be deposited. We sincerely regret any confusion that this error may have caused and, in particular, we regret that subsequent research efforts might have been unproductive as a result of our originally published findings. We therefore wish to retract this article.”