Abstract
Intestinal colonization by members of the family Enterobacteriaceae resistant to cefotaxime was surveyed for 3 years in a hematology-oncology unit. Of 416 patients, 66 (15.9%) were colonized, each with a different strain. The incidence of intestinal carriage was not correlated with cefotaxime consumption in the ward but was strongly associated with individual exposure to cefotaxime.
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- Andremont A., Sancho-Garnier H., Tancrede C. Epidemiology of intestinal colonization by members of the family Enterobacteriaceae highly resistant to erythromycin in a hematology-oncology unit. Antimicrob Agents Chemother. 1986 Jun;29(6):1104–1107. doi: 10.1128/aac.29.6.1104. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Benn R. A., Kemp R. J. Effect of antibiotic use on the incidence of cephalosporin resistance in two Australian hospitals. J Antimicrob Chemother. 1984 Sep;14 (Suppl B):71–76. doi: 10.1093/jac/14.suppl_b.71. [DOI] [PubMed] [Google Scholar]
- Collatz E., Gutmann L., Williamson R., Acar J. F. Development of resistance to beta-lactam antibiotics with special reference to third-generation cephalosporins. J Antimicrob Chemother. 1984 Sep;14 (Suppl B):13–21. doi: 10.1093/jac/14.suppl_b.13. [DOI] [PubMed] [Google Scholar]
- Guy H., Chavanet P., Portier H., Kazmierczak A., Cortet P. Traitement par une association céfotaxime-amikacine des épisodes infectieux des leucémies aiguës de l'adulte en aplasie thérapeutique. Nouv Presse Med. 1981 Feb 26;10(8):654–656. [PubMed] [Google Scholar]
- Jarlier V., Bismuth R., Nicolas M. H., Nguyen J., Truffot C., Grosset J. Survey of the phenotypes of susceptibility to beta-lactams in Enterobacteriaceae at the Pitie-Salpetriere Hospital. J Antimicrob Chemother. 1984 Sep;14 (Suppl B):59–65. doi: 10.1093/jac/14.suppl_b.59. [DOI] [PubMed] [Google Scholar]
- Lambert-Zechovsky N., Aufrant C., Bingen E., Blum C., Proux M. C., Mathieu H. Cefotaxime in children: efficacy, tolerance and effect on the intestinal bacterial flora. J Antimicrob Chemother. 1980 Sep;6 (Suppl A):235–242. doi: 10.1093/jac/6.suppl_a.235. [DOI] [PubMed] [Google Scholar]
- López E. L., Bonesana N. F., Rubeglio E., Schugurensky A., Sommersguter G., Grinstein S. Cefotaxime therapy in children with serious infections associated with reduced host defense mechanisms. J Antimicrob Chemother. 1980 Sep;6 (Suppl A):249–253. doi: 10.1093/jac/6.suppl_a.249. [DOI] [PubMed] [Google Scholar]
- Mitsuhashi S., Inoue M., Masuyoshi S. Antibacterial activity of cefotaxime. J Antimicrob Chemother. 1980 Sep;6 (Suppl A):37–46. doi: 10.1093/jac/6.suppl_a.37. [DOI] [PubMed] [Google Scholar]
- Nauciel C., Philippon A., Ronco E., Pilliot J., Guenounou M., Paul G., Brunel D., Outin H. D. Septicémies à Enterobacter cloacae et E. aerogenes: émergence de variants résistants (céphalosporinase déréprimée) en cours de traitement par des céphalosporines de troisième génération. Presse Med. 1985 Mar 23;14(12):673–676. [PubMed] [Google Scholar]
- Richmond M. H. beta-Lactamase stability of cefotaxime. J Antimicrob Chemother. 1980 Sep;6 (Suppl A):13–17. doi: 10.1093/jac/6.suppl_a.13. [DOI] [PubMed] [Google Scholar]
- Sanders C. C., Sanders W. E., Jr Emergence of resistance during therapy with the newer beta-lactam antibiotics: role of inducible beta-lactamases and implications for the future. Rev Infect Dis. 1983 Jul-Aug;5(4):639–648. doi: 10.1093/clinids/5.4.639. [DOI] [PubMed] [Google Scholar]
- Tancrede C. H., Andremont A. O., Leonard F. C. Epidemiology of enterobacteria resistant to cefotaxime in hospital. J Antimicrob Chemother. 1984 Sep;14 (Suppl B):53–57. doi: 10.1093/jac/14.suppl_b.53. [DOI] [PubMed] [Google Scholar]
- Tancrède C. H., Andremont A. O. Bacterial translocation and gram-negative bacteremia in patients with hematological malignancies. J Infect Dis. 1985 Jul;152(1):99–103. doi: 10.1093/infdis/152.1.99. [DOI] [PubMed] [Google Scholar]
- Wells C. L., Podzorski R. P., Peterson P. K., Ramsay N. K., Simmons R. L., Rhame F. S. Incidence of trimethoprim-sulfamethoxazole-resistant enterobacteriaceae among transplant recipients. J Infect Dis. 1984 Nov;150(5):699–706. doi: 10.1093/infdis/150.5.699. [DOI] [PubMed] [Google Scholar]