Skip to main content
Bulletin of the New York Academy of Medicine logoLink to Bulletin of the New York Academy of Medicine
. 1960 May;36(5):323–343.

Genetic Factors in Obesity*

Jean Mayer
PMCID: PMC1806342  PMID: 19312652

Full text

PDF
323

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ALONSO L. G., MAREN T. H. Effect of food restriction on body composition of hereditary obese mice. Am J Physiol. 1955 Nov;183(2):284–290. doi: 10.1152/ajplegacy.1955.183.2.284. [DOI] [PubMed] [Google Scholar]
  2. ANLIKER J., MAYER J. An operant conditioning technique for studying feeding-fasting patterns in normal and obese mice. J Appl Physiol. 1956 May;8(6):667–670. doi: 10.1152/jappl.1956.8.6.667. [DOI] [PubMed] [Google Scholar]
  3. ANLIKER J., MAYER J. The regulation of food intake; some experiments relating behavioral, metabolic and morphologic aspects. Am J Clin Nutr. 1957 Mar-Apr;5(2):148–153. doi: 10.1093/ajcn/5.2.148. [DOI] [PubMed] [Google Scholar]
  4. BATES M. W., NAUSS S. F., HAGMAN N. C., MAYER J. Fat metabolism in three forms of experimental obesity; body composition. Am J Physiol. 1955 Feb;180(2):301–303. doi: 10.1152/ajplegacy.1955.180.2.301. [DOI] [PubMed] [Google Scholar]
  5. BATES M. W., ZOMZELY C., MAYER J. Fat metabolism in three forms of experimental obesity. IV. Instantaneous rates of lipogenesis in vivo. Am J Physiol. 1955 Apr;181(1):187–190. doi: 10.1152/ajplegacy.1955.181.1.187. [DOI] [PubMed] [Google Scholar]
  6. BIELSCHOWSKY F., BIELSCHOWSKY M. The New Zealand strain of obese mice; their response to stilboestrol and to insulin. Aust J Exp Biol Med Sci. 1956 Jun;34(3):181–198. doi: 10.1038/icb.1956.22. [DOI] [PubMed] [Google Scholar]
  7. CAHILL G., Jr, GADSDEN E. L., MAYER J., SHULL K. H. Glucose-6-phosphatase and phosphorylase activities in mice bearing corticotropin-secreting tumors. J Biol Chem. 1956 Sep;222(1):415–420. [PubMed] [Google Scholar]
  8. CARPENTER K. J., MAYER J. Physiologic observations on yellow obesity in the mouse. Am J Physiol. 1958 Jun;193(3):499–504. doi: 10.1152/ajplegacy.1958.193.3.499. [DOI] [PubMed] [Google Scholar]
  9. CHRISTOPHE J., MAYER J. Effects of chronic treatment with carbutamide on distribution and biosynthesis of fatty acids and cholesterol in obese-hyperglycemic mice. Am J Physiol. 1959 Mar;196(3):603–606. doi: 10.1152/ajplegacy.1959.196.3.603. [DOI] [PubMed] [Google Scholar]
  10. Castle W E. Influence of Certain Color Mutations on Body Size in Mice, Rats, and Rabbits. Genetics. 1941 Mar;26(2):177–191. doi: 10.1093/genetics/26.2.177. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. DAVIS T. R., MAYER J. Imperfect homeothermia in the hereditary obese-hyperglycemic syndrome of mice. Am J Physiol. 1954 May;177(2):222–226. doi: 10.1152/ajplegacy.1954.177.2.222. [DOI] [PubMed] [Google Scholar]
  12. DAVIS T. R., MAYER J. Use of high frequency electromagnetic waves in the study of thermogenesis. Am J Physiol. 1954 Aug;178(2):283–287. doi: 10.1152/ajplegacy.1954.178.2.283. [DOI] [PubMed] [Google Scholar]
  13. FENTON P. F., CHASE H. B. Effect of diet on obesity of yellow mice in inbred lines. Proc Soc Exp Biol Med. 1951 Jul;77(3):420–422. doi: 10.3181/00379727-77-18800. [DOI] [PubMed] [Google Scholar]
  14. FENTON P. F., DOWLING M. T. Studies on obesity. I. Nutritional obesity in mice. J Nutr. 1953 Feb 10;49(2):319–331. doi: 10.1093/jn/49.2.319. [DOI] [PubMed] [Google Scholar]
  15. FRY P. C. A comparative study of obese children selected on the basis of fat pads. J Clin Nutr. 1953 Sep-Oct;1(6):453–468. doi: 10.1093/ajcn/1.6.453. [DOI] [PubMed] [Google Scholar]
  16. GOLDBERG R. C., MAYER J. Normal iodine uptake and anoxia resistance accompanying apparent hypometabolism in hereditary obese-hyperglycemic syndrome. Proc Soc Exp Biol Med. 1952 Oct;81(1):323–325. doi: 10.3181/00379727-81-19865. [DOI] [PubMed] [Google Scholar]
  17. GUGGENHEIM K., MAYER J. Studies of pyruvate and acetate metabolism in the hereditary obesity-diabetes syndrome of mice. J Biol Chem. 1952 Sep;198(1):259–265. [PubMed] [Google Scholar]
  18. INGALLS A. M., DICKIE M. M., SNELL G. D. Obese, a new mutation in the house mouse. J Hered. 1950 Dec;41(12):317–318. doi: 10.1093/oxfordjournals.jhered.a106073. [DOI] [PubMed] [Google Scholar]
  19. IVERSEN T. Psychogenic obesity in children. I. Acta Paediatr. 1953 Jan;42(1):8–19. doi: 10.1111/j.1651-2227.1953.tb05560.x. [DOI] [PubMed] [Google Scholar]
  20. JEHL J., MAYER J., McKEE R. W. Influence of the hereditary obese-hyperglycemic syndrome and of alloxan diabetes on the survival of mice with Ehrlich ascites carcinoma. Cancer Res. 1955 Jun;15(5):341–343. [PubMed] [Google Scholar]
  21. JOHNSON M. L., BURKE B. S., MAYER J. Relative importance of inactivity and overeating in the energy balance of obese high school girls. Am J Clin Nutr. 1956 Jan-Feb;4(1):37–44. doi: 10.1093/ajcn/4.1.37. [DOI] [PubMed] [Google Scholar]
  22. MAYER J., ANDRUS S. B., SILIDES D. J. Effect of diethyldithiocarbamate and other agents on mice with the obese-hyperglycemic syndrome. Endocrinology. 1953 Nov;53(5):572–581. doi: 10.1210/endo-53-5-572. [DOI] [PubMed] [Google Scholar]
  23. MAYER J., BARRNETT R. J. Sensitivity to cold in the hereditary obese-hyperglycemic syndrome of mice. Yale J Biol Med. 1953 Sep;26(1):38–45. [PMC free article] [PubMed] [Google Scholar]
  24. MAYER J., DICKIE M. M., BATES M. W., VITALE J. J. Free selection of nutrients by hereditarily obese mice. Science. 1951 Jun 29;113(2948):745–746. doi: 10.1126/science.113.2948.745-a. [DOI] [PubMed] [Google Scholar]
  25. MAYER J. Decreased activity and energy balance in the hereditary obesity-diabetes syndrome of mice. Science. 1953 May 8;117(3045):504–505. doi: 10.1126/science.117.3045.504. [DOI] [PubMed] [Google Scholar]
  26. MAYER J. Genetic, traumatic and environmental factors in the etiology of obesity. Physiol Rev. 1953 Oct;33(4):472–508. doi: 10.1152/physrev.1953.33.4.472. [DOI] [PubMed] [Google Scholar]
  27. MAYER J., HAGMAN N. C., MARSHALL N. B., STOOPS A. J. Fat metabolism in three forms of obesity. V. Hepatic lipogenesis in vitro. Am J Physiol. 1955 Jun;181(3):501–503. doi: 10.1152/ajplegacy.1955.181.3.501. [DOI] [PubMed] [Google Scholar]
  28. MAYER J., HAGMAN N. C. Total body water and blood volume in hereditary obese-hyperglycemic syndrome of mice. Proc Soc Exp Biol Med. 1953 Apr;82(4):647–649. doi: 10.3181/00379727-82-20206. [DOI] [PubMed] [Google Scholar]
  29. MAYER J., JONES A. K. Hypercholesteremia in the hereditary obese-hyperglycemic syndrome of mice. Am J Physiol. 1953 Dec;175(3):339–342. doi: 10.1152/ajplegacy.1953.175.3.339. [DOI] [PubMed] [Google Scholar]
  30. MAYER J. Obesity: psychologic aspects and therapy. Postgrad Med. 1959 Jun;25(6):739–746. doi: 10.1080/00325481.1959.11712496. [DOI] [PubMed] [Google Scholar]
  31. MAYER J., ROY P., MITRA K. P. Relation between caloric intake, body weight, and physical work: studies in an industrial male population in West Bengal. Am J Clin Nutr. 1956 Mar-Apr;4(2):169–175. doi: 10.1093/ajcn/4.2.169. [DOI] [PubMed] [Google Scholar]
  32. MAYER J., RUSSELL R. E., BATES M. W., DICKIE M. M. Basal oxygen consumption of hereditarily obese and diabetic mice. Endocrinology. 1952 Mar;50(3):318–323. doi: 10.1210/endo-50-3-318. [DOI] [PubMed] [Google Scholar]
  33. MAYER J., RUSSELL R. E., BATES M. W., DICKIE M. M. Metabolic, nutritional and endocrine studies of the hereditary obesity-diabetes syndrome of mice and mechanism of its development. Metabolism. 1953 Jan;2(1):9–21. [PubMed] [Google Scholar]
  34. MAYER J., SILIDES D. J. Fat metabolism in experimental obesities. VIII. Blood total lipids and ketones in four kinds of obese mice. Experientia. 1958 Mar 15;14(3):96–99. doi: 10.1007/BF02159235. [DOI] [PubMed] [Google Scholar]
  35. MAYER J., SILIDES D. N. A quantitative method of determination of the diabetogenic activity of growth hormone preparations. Endocrinology. 1953 Jan;52(1):54–56. doi: 10.1210/endo-52-1-54. [DOI] [PubMed] [Google Scholar]
  36. MAYER J. Some advances in the study of the physiologic basis of obesity. Metabolism. 1957 Sep;6(5):435–446. [PubMed] [Google Scholar]
  37. MAYER J. The physiological basis of obesity and leanness. Part II. Nutr Abstr Rev. 1955 Oct;25(4):871–883. [PubMed] [Google Scholar]
  38. MAYER J., YANNONI C. Z. Increased intestinal absorption of glucose in three forms of obesity in the mouse. Am J Physiol. 1956 Apr;185(1):49–53. doi: 10.1152/ajplegacy.1956.185.1.49. [DOI] [PubMed] [Google Scholar]
  39. MAYER J., ZOMZELY C., STARE F. J. Lack of effect of exercise on serum cholesterol levels in two types of experimental obesity. Experientia. 1957 Jun 15;13(6):250–251. doi: 10.1007/BF02157443. [DOI] [PubMed] [Google Scholar]
  40. MICKELSEN O., TAKAHASHI S., CRAIG C. Experimental obesity. I. Production of obesity in rats by feeding high-fat diets. J Nutr. 1955 Dec 10;57(4):541–554. doi: 10.1093/jn/57.4.541. [DOI] [PubMed] [Google Scholar]
  41. MORSE W. I., HERRERA ACENA G., MAYER J. Electrolyte and water composition of muscle and liver in hereditary obese-hyperglycemic syndrome of mice. Proc Soc Exp Biol Med. 1955 Oct;90(1):199–202. doi: 10.3181/00379727-90-21981. [DOI] [PubMed] [Google Scholar]
  42. SHULL K. H., ASHMORE J., MAYER J. Hexokinase, glucose-6-phosphatase and phosphorylase levels in hereditarily obese-hyperglycemic mice. Arch Biochem Biophys. 1956 May;62(1):210–216. doi: 10.1016/0003-9861(56)90104-7. [DOI] [PubMed] [Google Scholar]
  43. SHULL K. H., MAYER J. Analysis of the blood sugar response of obese-hyperglycemic mice and normal mice to hormones: insulin, glucagon, and epinephrine. Endocrinology. 1956 Feb;58(2):220–225. doi: 10.1210/endo-58-2-220. [DOI] [PubMed] [Google Scholar]
  44. SHULL K. H., MAYER J. The turnover of liver glycogen in obese hyperglycemic mice. J Biol Chem. 1956 Feb;218(2):885–896. [PubMed] [Google Scholar]
  45. SILIDES D. J., MAYER J. Effect of hormonal and dietary treatments on lipogenesis from acetate in hereditarily obese hyperglycemic mice. Experientia. 1956 Feb 15;12(2):66–67. doi: 10.1007/BF02164682. [DOI] [PubMed] [Google Scholar]
  46. SUDSANEH S., MAYER J. Relation of metabolic events to gastric contractions in the rat. Am J Physiol. 1959 Aug;197:269–273. doi: 10.1152/ajplegacy.1959.197.2.269. [DOI] [PubMed] [Google Scholar]
  47. THOMPSON M. M., MAYER J. Hypoglycemic effects of saccharin in experimental animals. Am J Clin Nutr. 1959 Jan-Feb;7(1):80–85. doi: 10.1093/ajcn/7.1.80. [DOI] [PubMed] [Google Scholar]
  48. WOLFFE J. B., HYMAN A. S., PLUNGIAN M. B., DALE A. D., McGINNIS G. E., WALKOW M. B. Studies in experimental atheromatosis; atheromatosis and hepato-atherosis in geese; possible reversibility and clinical implications. J Gerontol. 1952 Jan;7(1):13–23. doi: 10.1093/geronj/7.1.13. [DOI] [PubMed] [Google Scholar]
  49. WRENSHALL G. A., ANDRUS S. B., MAYER J. High levels of pancreatic insulin coexistent with hyperplasia and degranulation of beta cells in mice with the hereditary obese-hyperglycemic syndrome. Endocrinology. 1955 Mar;56(3):335–340. doi: 10.1210/endo-56-3-335. [DOI] [PubMed] [Google Scholar]
  50. ZOMZELY C., MAYER J. Endogenous dilution of administered labeled acetate during lipogenesis and cholesterogenesis in two types of obese mice. Am J Physiol. 1959 May;196(5):956–960. doi: 10.1152/ajplegacy.1959.196.5.956. [DOI] [PubMed] [Google Scholar]
  51. ZOMZELY C., MAYER J. Fat metabolism in experimental obesities. IX. Lipogenesis and cholesterogenesis in yellow obese mice. Am J Physiol. 1959 Mar;196(3):611–613. doi: 10.1152/ajplegacy.1959.196.3.611. [DOI] [PubMed] [Google Scholar]

Articles from Bulletin of the New York Academy of Medicine are provided here courtesy of New York Academy of Medicine

RESOURCES