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. 1981 Feb;19(2):213–217. doi: 10.1128/aac.19.2.213

Inhibition of vaccinia virus maturation by zinc chloride.

E Katz, E Margalith
PMCID: PMC181396  PMID: 7347557

Abstract

Zinc chloride (0.1 mM) inhibited by 96.4% the growth of vaccinia virus in HeLa cells. Approximately 50% inhibition in formation of particles that sedimented in sucrose gradients similarly to vaccinia virions occurred in the presence of zinc ions. Whereas the synthesis of the viral deoxyribonucleic acid was not affected by zinc chloride, a decrease in the overall synthesis of viral polypeptides and inhibition of the cleavage of precursors to the core polypeptides were observed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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